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Ion Interference Therapy of Tumors Based on Inorganic Nanoparticles

文献类型：期刊论文

作者Chi, Yongjie1,2; Sun, Peng1,3; Gao, Yuan1,4; Zhang, Jing1,2; Wang, Lianyan1,2
刊名BIOSENSORS-BASEL
出版日期2022-02-01
卷号12期号:2页码:14
关键词ion interference therapy cancer ions inorganic nanoparticles
DOI10.3390/bios12020100
英文摘要As an essential substance for cell life activities, ions play an important role in controlling cell osmotic pressure balance, intracellular acid-base balance, signal transmission, biocatalysis and so on. The imbalance of ion homeostasis in cells will seriously affect the activities of cells, cause irreversible damage to cells or induce cell death. Therefore, artificially interfering with the ion homeostasis in tumor cells has become a new means to inhibit the proliferation of tumor cells. This treatment is called ion interference therapy (IIT). Although some molecular carriers of ions have been developed for intracellular ion delivery, inorganic nanoparticles are widely used in ion interference therapy because of their higher ion delivery ability and higher biocompatibility compared with molecular carriers. This article reviewed the recent development of IIT based on inorganic nanoparticles and summarized the advantages and disadvantages of this treatment and the challenges of future development, hoping to provide a reference for future research.
WOS关键词CALCIUM ; OVERLOAD
资助项目National Natural Science Foundation of China[81973262] ; National Natural Science Foundation of China[82011530138] ; National Natural Science Foundation of China[81970660]
WOS研究方向Chemistry ; Science & Technology - Other Topics ; Instruments & Instrumentation
语种英语
WOS记录号WOS:000767769300001
出版者MDPI
资助机构National Natural Science Foundation of China
源URL[http://ir.ipe.ac.cn/handle/122111/52198]  
专题中国科学院过程工程研究所
通讯作者Wang, Lianyan
作者单位1.Chinese Acad Sci, Inst Proc Engn, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100190, Peoples R China
3.Shenyang Agr Univ, Coll Biol Sci & Technol, Shenyang 110866, Peoples R China
4.Northeast Forestry Univ, Key Lab Forest Plant Ecol, Minist Educ, Coll Chem Chem Engn & Resource Utilizat, Harbin 150040, Peoples R China
推荐引用方式
GB/T 7714		 Chi, Yongjie,Sun, Peng,Gao, Yuan,et al. Ion Interference Therapy of Tumors Based on Inorganic Nanoparticles[J]. BIOSENSORS-BASEL,2022,12(2):14.
APA Chi, Yongjie,Sun, Peng,Gao, Yuan,Zhang, Jing,&Wang, Lianyan.(2022).Ion Interference Therapy of Tumors Based on Inorganic Nanoparticles.BIOSENSORS-BASEL,12(2),14.
MLA Chi, Yongjie,et al."Ion Interference Therapy of Tumors Based on Inorganic Nanoparticles".BIOSENSORS-BASEL 12.2(2022):14.

入库方式： OAI收割

来源：过程工程研究所

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