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Determination of the heating efficiency of magnetotactic bacteria in alternating magnetic field

文献类型：期刊论文

作者Zhang, Tongwei1,2,3,4; Xu, Huangtao1,2,3,4; Liu, Jia1,3,4; Pan, Yongxin1,2,3,4; Cao, Changqian1,3,4
刊名JOURNAL OF OCEANOLOGY AND LIMNOLOGY
出版日期2021-11-01
卷号39期号:6页码:2116-2126
关键词magnetotactic bacteria (MTB) hyperthermia rock magnetism alternating magnetic field (AMF)
ISSN号2096-5508
DOI10.1007/s00343-021-1071-4
英文摘要Magnetotactic bacteria (MTB) intact cells have been applied in magnetic hyperthermia therapy of tumor, showing great efficiency in heating for tumor cell inhibition. However, the detailed magnetic hyperthermia properties and optimum heat production conditions of MTB cells are still poorly understood due to lack of standard measuring equipment. The specific absorption rate (SAR) of MTB cells is often measured by home-made equipment at a limited frequency and magnetic field amplitude. In this study, we have used a commercial standard system to implement a comprehensive study of the hyperthermic response of Magnetospirillum gryphiswaldense MSR-1 strain under 7 frequencies of 144-764 kHz, and 8 field amplitudes between 10 and 45 kA/m. The measurement results prove that the SAR of MTB cells increases with magnetic field frequency and amplitude within a certain range. In combination with the magnetic measurements, it is determined that the magnetic hyperthermia mechanism of MTB mainly follows the principle of hysteresis loss, and the heat efficiency of MTB cells in alternating magnetic field are mainly aff ected by three parameters of hysteresis loop, saturation magnetisation, saturation remanent magnetisation, and coercivity. Thus when we culture MTB in LA-2 medium containing sodium nitrate as source of nitrogen, the SAR of MTBLA-2 cells with magnetosomes arranged in chains can be as high as 4 925.6 W/g (in this work, all SARs are calculated with iron mass) under 764 kHz and 30 kA/m, which is 7.5 times than current commercial magnetic particles within similar size range.
WOS关键词MAGNETOSPIRILLUM-GRYPHISWALDENSE MSR-1 ; MAGNETOSOME FORMATION ; NANOPARTICLES ; HYPERTHERMIA ; GROWTH ; CELLS
资助项目Strategic Priority Research Program of Chinese Academy of Sciences[XDB41010403] ; National Natural Science Foundation of China[41804070] ; National Natural Science Foundation of China[41774076] ; National Natural Science Foundation of China[41621004] ; Key Program of Chinese Academy of Sciences[QYZDJ-SSWDQC024] ; Key Research Program of the Institute of Geology and Geophysics, CAS[IGGCAS-201903] ; PetroChina Innovation Foundation[2020D-5007-0105]
WOS研究方向Marine & Freshwater Biology ; Oceanography
语种英语
WOS记录号WOS:000734164300012
出版者SCIENCE PRESS
资助机构Strategic Priority Research Program of Chinese Academy of Sciences ; Strategic Priority Research Program of Chinese Academy of Sciences ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Key Program of Chinese Academy of Sciences ; Key Program of Chinese Academy of Sciences ; Key Research Program of the Institute of Geology and Geophysics, CAS ; Key Research Program of the Institute of Geology and Geophysics, CAS ; PetroChina Innovation Foundation ; PetroChina Innovation Foundation ; Strategic Priority Research Program of Chinese Academy of Sciences ; Strategic Priority Research Program of Chinese Academy of Sciences ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Key Program of Chinese Academy of Sciences ; Key Program of Chinese Academy of Sciences ; Key Research Program of the Institute of Geology and Geophysics, CAS ; Key Research Program of the Institute of Geology and Geophysics, CAS ; PetroChina Innovation Foundation ; PetroChina Innovation Foundation ; Strategic Priority Research Program of Chinese Academy of Sciences ; Strategic Priority Research Program of Chinese Academy of Sciences ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Key Program of Chinese Academy of Sciences ; Key Program of Chinese Academy of Sciences ; Key Research Program of the Institute of Geology and Geophysics, CAS ; Key Research Program of the Institute of Geology and Geophysics, CAS ; PetroChina Innovation Foundation ; PetroChina Innovation Foundation ; Strategic Priority Research Program of Chinese Academy of Sciences ; Strategic Priority Research Program of Chinese Academy of Sciences ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; Key Program of Chinese Academy of Sciences ; Key Program of Chinese Academy of Sciences ; Key Research Program of the Institute of Geology and Geophysics, CAS ; Key Research Program of the Institute of Geology and Geophysics, CAS ; PetroChina Innovation Foundation ; PetroChina Innovation Foundation
源URL[http://ir.iggcas.ac.cn/handle/132A11/103957]  
专题地质与地球物理研究所_中国科学院地球与行星物理重点实验室
通讯作者Cao, Changqian
作者单位1.Chinese Acad Sci, Innovat Acad Earth Sci, Beijing 100029, Peoples R China
2.Univ Chinese Acad Sci, Coll Earth & Planetary Sci, Beijing 100049, Peoples R China
3.Chinese Acad Sci, France China Joint Lab Evolut & Dev Magnetotact M, Beijing 100029, Peoples R China
4.Chinese Acad Sci, Innovat Acad Earth Sci, Inst Geol & Geophys, Key Lab Earth & Planetary Phys, Beijing 100029, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Tongwei,Xu, Huangtao,Liu, Jia,et al. Determination of the heating efficiency of magnetotactic bacteria in alternating magnetic field[J]. JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2021,39(6):2116-2126.
APA Zhang, Tongwei,Xu, Huangtao,Liu, Jia,Pan, Yongxin,&Cao, Changqian.(2021).Determination of the heating efficiency of magnetotactic bacteria in alternating magnetic field.JOURNAL OF OCEANOLOGY AND LIMNOLOGY,39(6),2116-2126.
MLA Zhang, Tongwei,et al."Determination of the heating efficiency of magnetotactic bacteria in alternating magnetic field".JOURNAL OF OCEANOLOGY AND LIMNOLOGY 39.6(2021):2116-2126.

入库方式： OAI收割

来源：地质与地球物理研究所

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