Evolutionary patterns of genic DNA methylation vary across land plants
文献类型：期刊论文
| 作者 | Takuno, Shohei; Ran, Jin-Hua; Gaut, Brandon S. |
| 刊名 | NATURE PLANTS
 |
| 出版日期 | 2016 |
| 卷号 | 2期号:2 |
| ISSN号 | 2055-026X |
| DOI | 10.1038/NPLANTS.2015.222 |
| 文献子类 | Article |
| 英文摘要 | Little is known about patterns of genic DNA methylation across the plant kingdom or about the evolutionary processes that shape them. To characterize gene-body methylation (gbM) within exons, we have gathered single-base resolution methylome data that span the phylogenetic breadth of land plants. We find that a basal land plant, Marchantia polymorpha, lacks any evident signal of gbM within exons, but conifers have high levels of both CG and CHG (where H is A, C or T) methylation in expressed genes. To begin to understand the evolutionary forces that shape gbM, we first tested for correlations in methylation levels across orthologues(1,2). Genic CG methylation levels, but not CHG or CHH levels, are correlated across orthologues for species as distantly related as ferns and angiosperms. Hence, relative levels of CG methylation are a consistent property across genes, even for species that diverged similar to 400 million years ago(3,4). In contrast, genic CHG methylation correlates with genome size, suggesting that the host epigenetic response to transposable elements also affects genes. Altogether, our data indicate that the evolutionary forces acting on DNA methylation vary substantially across species, genes and methylation contexts. |
| 学科主题 | Plant Sciences |
| 出版地 | LONDON |
| 电子版国际标准刊号 | 2055-0278 |
| WOS关键词 | CYTOSINE METHYLATION ; GENOME ; REVEALS ; EPIGENOME ; GENES ; SITES |
| WOS研究方向 | Science Citation Index Expanded (SCI-EXPANDED) |
| 语种 | 英语 |
| WOS记录号 | WOS:000375393200008 |
| 出版者 | NATURE PUBLISHING GROUP |
| 资助机构 | SOKENDAI ; JSPSMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of Science [15K18585] ; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31330008] ; NSFNational Science Foundation (NSF) [IOS-1542703] ; Direct For Biological SciencesNational Science Foundation (NSF)NSF - Directorate for Biological Sciences (BIO) [1542703] Funding Source: National Science Foundation |
| 源URL | [http://ir.ibcas.ac.cn/handle/2S10CLM1/25068]  |
| 专题 | 植物研究所_系统与进化植物学研究中心_系统与进化植物学研究中心_学位论文 |
| 作者单位 | 1.Grad Univ Adv Studies, SOKENDAI, Hayama, Kanagawa 2400193, Japan 2.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary Bot, Beijing, Peoples R China 3.Ran, Jin-Hua; Gaut, Brandon S.] Univ Calif Irvine, Dept Ecol & Evolutionary Biol, 321 Steinhaus Hall, Irvine, CA 92697 USA |
| 推荐引用方式 GB/T 7714 | Takuno, Shohei,Ran, Jin-Hua,Gaut, Brandon S.. Evolutionary patterns of genic DNA methylation vary across land plants[J]. NATURE PLANTS,2016,2(2). |
| APA | Takuno, Shohei,Ran, Jin-Hua,&Gaut, Brandon S..(2016).Evolutionary patterns of genic DNA methylation vary across land plants.NATURE PLANTS,2(2). |
| MLA | Takuno, Shohei,et al."Evolutionary patterns of genic DNA methylation vary across land plants".NATURE PLANTS 2.2(2016). |
入库方式： OAI收割
来源：植物研究所
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