Module-Fluidics: Building Blocks for Spatio-Temporal Microenvironment Control
文献类型：期刊论文
| 作者 | Ling, Bowen1,2; Battiato, Ilenia2 |
| 刊名 | MICROMACHINES
 |
| 出版日期 | 2022-05-01 |
| 卷号 | 13期号:5页码:8 |
| 关键词 | mircofluidics micromodel microfluidic valve |
| DOI | 10.3390/mi13050774 |
| 通讯作者 | Battiato, Ilenia(ibattiat@stanford.edu) |
| 英文摘要 | Generating the desired solute concentration signal in micro-environments is vital to many applications ranging from micromixing to analyzing cellular response to a dynamic microenvironment. We propose a new modular design to generate targeted temporally varying concentration signals in microfluidic systems while minimizing perturbations to the flow field. The modularized design, here referred to as module-fluidics, similar in principle to interlocking toy bricks, is constructed from a combination of two building blocks and allows one to achieve versatility and flexibility in dynamically controlling input concentration. The building blocks are an oscillator and an integrator, and their combination enables the creation of controlled and complex concentration signals, with different user-defined time-scales. We show two basic connection patterns, in-series and in-parallel, to test the generation, integration, sampling and superposition of temporally-varying signals. All such signals can be fully characterized by analytic functions, in analogy with electric circuits, and allow one to perform design and optimization before fabrication. Such modularization offers a versatile and promising platform that allows one to create highly customizable time-dependent concentration inputs which can be targeted to the specific application of interest. |
| WOS关键词 | MICROMIXERS ; COMPLEX |
| 资助项目 | Department of Energy[DE-SC0014227] |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Instruments & Instrumentation ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000803291200001 |
| 资助机构 | Department of Energy |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/89525]  |
| 专题 | 力学研究所_流固耦合系统力学重点实验室(2012-) |
| 通讯作者 | Battiato, Ilenia |
| 作者单位 | 1.Chinese Acad Sci, Inst Mech, Beijing 100190, Peoples R China 2.Stanford Univ, Energy Resource Engn, Stanford, CA 94305 USA |
| 推荐引用方式 GB/T 7714 | Ling, Bowen,Battiato, Ilenia. Module-Fluidics: Building Blocks for Spatio-Temporal Microenvironment Control[J]. MICROMACHINES,2022,13(5):8. |
| APA | Ling, Bowen,&Battiato, Ilenia.(2022).Module-Fluidics: Building Blocks for Spatio-Temporal Microenvironment Control.MICROMACHINES,13(5),8. |
| MLA | Ling, Bowen,et al."Module-Fluidics: Building Blocks for Spatio-Temporal Microenvironment Control".MICROMACHINES 13.5(2022):8. |
入库方式： OAI收割
来源：力学研究所
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