Interaction between the BDNF rs11030101 genotype and job stress on cognitive empathy
文献类型：期刊论文
| 作者 | Duan, Yuzhong8; Li, Yuling7; Yun, Hanqi6; Kaplan, Andrew M.5; Kennedy, Alexis5; Dong, Yan3,4; He, Shu-chang2,7; Zhang, Xiang Yang1,6
|
| 刊名 | JOURNAL OF AFFECTIVE DISORDERS
 |
| 出版日期 | 2022-07-01 |
| 卷号 | 308页码:442-448 |
| 关键词 | Cognitive empathy Job stress BDNF rs11030101 G x E interaction |
| ISSN号 | 0165-0327 |
| DOI | 10.1016/j.jad.2022.04.054 |
| 通讯作者 | Dong, Yan(dong8958@126.com) ; He, Shu-chang(shuchangh@pku.edu.cn) ; Zhang, Xiang Yang(zhangxy@psych.ac.cn) |
| 英文摘要 | Background: Empathy refers to an individual's ability to experience the emotional and cognitive processes of another person during social interactions. Although many studies have examined the effects of genetic variation on emotional empathy, little is currently known about whether genetic factors may influence cognitive empathy. This study investigated the relationship between BDNF rs11030101 genotype, job stress, and empathy, especially cognitive empathy, in a Chinese Han population.& nbsp;Methods: A cross-sectional design was used and 340 participants were recruited from a university in Beijing. Interpersonal Reactivity Index (IRI) was used to measure empathy. Job stress was measured using House and Rizzo's Job Stress Scale. The BDNF rs11030101 was genotyped in all participants.& nbsp;Results: Gender and age were associated with various IRI subscales (p < 0.001). After controlling for gender, age and education level, BDNF rs11030101 genotype had no main effect on all empathy subscales (p > 0.05). Job stress was negatively associated with Perspective Taking (p = 0.006) and positively associated with Personal Distress (p < 0.001). In addition, the BDNF rs11030101 genotype modulated the relationship between job stress and Fantasy (p = 0.013), indicating that T allele carriers had higher Fantasy scores at higher job stress and lower Fantasy scores at lower job stress than AA homozygotes. This interaction was only present in women. Limitations: The sample size and single-nucleotide polymorphism are limited, and the cross-sectional design should be improved.& nbsp;Conclusions: Female university faculty with the BDNF rs11030101 T allele may utilize higher emotional job demands, thereby fostering their cognitive empathy. |
| 收录类别 | SCI |
| WOS关键词 | GENE ; POLYMORPHISM ; DISORDER |
| 资助项目 | National Natural Science Foundation of China[81871060] |
| WOS研究方向 | Neurosciences & Neurology ; Psychiatry |
| 语种 | 英语 |
| WOS记录号 | WOS:000795943800007 |
| 出版者 | ELSEVIER |
| 资助机构 | National Natural Science Foundation of China |
| 源URL | [http://ir.psych.ac.cn/handle/311026/42758]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 通讯作者 | Dong, Yan; He, Shu-chang; Zhang, Xiang Yang |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, 16 Lincui Rd, Beijing 100101, Peoples R China 2.Peking Univ, 5 Yiheyuan Rd, Beijing 100871, Peoples R China 3.Renmin Univ China, 59 Zhongguancun Ave, Beijing 100871, Peoples R China 4.Renmin Univ China, Dept Psychol, Beijing, Peoples R China 5.Univ Texas Hlth Sci Ctr, Dept Psychiat & Behav Sci, Houston, TX USA 6.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Healthy, Beijing, Peoples R China 7.Peking Univ, Sch Psychol & Cognit Sci, Beijing Key Lab Behav & Mental Hlth, Beijing, Peoples R China 8.PLA Strateg Support Force Med Ctr, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 |
Duan, Yuzhong,Li, Yuling,Yun, Hanqi,et al. Interaction between the BDNF rs11030101 genotype and job stress on cognitive empathy [J]. JOURNAL OF AFFECTIVE DISORDERS,2022,308:442-448. |
| APA |
Duan, Yuzhong.,Li, Yuling.,Yun, Hanqi.,Kaplan, Andrew M..,Kennedy, Alexis.,...&Zhang, Xiang Yang.(2022). Interaction between the BDNF rs11030101 genotype and job stress on cognitive empathy .JOURNAL OF AFFECTIVE DISORDERS,308,442-448. |
| MLA |
Duan, Yuzhong,et al." Interaction between the BDNF rs11030101 genotype and job stress on cognitive empathy ".JOURNAL OF AFFECTIVE DISORDERS 308(2022):442-448. |
入库方式： OAI收割
来源：心理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。