Exploration of cortical inhibition and habituation in insomnia: Based on CNV and EEG
文献类型:期刊论文
作者 | Zhang, Xiao6; Liu, Xinrui5; Wang, Yan3,4; Liu, Chang6; Zhang, Ning2; Lu, Jun1; Lv, Yudan6 |
刊名 | METHODS |
出版日期 | 2022-08-01 |
卷号 | 204页码:73-83 |
ISSN号 | 1046-2023 |
关键词 | Insomnia Cognitive dysfunction CNV FFT Ceiling theory |
DOI | 10.1016/j.ymeth.2022.01.012 |
通讯作者 | Lv, Yudan(lvyudan@sina.com) |
英文摘要 | Objective: Cognitive dysfunction with abnormal cortical inhibition and habituation has frequently been found in patients with insomnia. And the so-called contingent negative variation (CNV) and EEG power spectral density (FFT) may be the best choice to explore the underlining pathophysiology.Methods: We used polysomnography (PSG) to record such objective PSG parameters. The amplitudes, latencies, areas of different CNV components such as oCNV, iCNV and tCNV, PINV have been selected and analyzed. Behavioral data such as manual reaction time (RT) has been analyzed. Spectral analysis was performed with fast Fourier transformation (FFT) on all channels to make a spectral analyses of EEG datas.Results: The A-latency located in CZ or PZ were statistically longer in insomnia group than control group, the iCNV-latency located in insomnia group were statistically shorter than control group. The iCNV-amplitude located in insomnia group was lower than control group. The oCNV-amplitude or the tCNV-amplitude located in insomnia group was higher than control group. The oCNV-square, tCNV-square, or PINV-square located in insomnia group were significant larger than control group. 131 or 132 activity distributed in bilateral hemisphere were significantly increased in insomnia group than control group with different distributions.Discussion: Our study revealed varied attentional and information processing in insomnia patients. Above all, we made a hypothesis with ceiling theory: Frontal lobe play an important role in maintaining cognitive processing, which needs much more energy consumption and leads to decreased fast EEG activity in frontal cortex, which contributes to reduced cortical inhibition, represented as abnormal CNV. |
收录类别 | SCI |
WOS关键词 | CONTINGENT NEGATIVE-VARIATION ; EVOKED POTENTIALS ; BRAIN ACTIVITY ; OSCILLATIONS ; CORTEX ; SLEEP |
资助项目 | Transformation Fund of the Jilin University First Hospital[JDYY2021-A0018] ; Jilin Provincial science and technology Fund[20210402022GH] ; Beijing Municipal Science and Tech Commission[Z171100000117004] ; Beijing Municipal Science and Tech Commission[Z161100002616013] |
WOS研究方向 | Biochemistry & Molecular Biology |
语种 | 英语 |
出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
WOS记录号 | WOS:000809912400009 |
资助机构 | Transformation Fund of the Jilin University First Hospital ; Jilin Provincial science and technology Fund ; Beijing Municipal Science and Tech Commission |
源URL | [http://ir.psych.ac.cn/handle/311026/42817] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Lv, Yudan |
作者单位 | 1.Harvard Med Sch, Beth Israel Deaconess Med Ctr, Dept Neurol, Boston, MA USA 2.Yantai Penglai Hosp Tradit Chinese Med, Dept Intens Care Unit, Yantai, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China 4.Chinese Acad Sci, Inst Psychol, Ctr Aging Psychol, Key Lab Mental Hlth, Beijing, Peoples R China 5.Jilin Univ, Hosp 1, Dept Neurosurg, 71-Xinmin St, Changchun, Peoples R China 6.Jilin Univ, Hosp 1, Neurosci Ctr, Dept Neurol, 71-Xinmin St, Changchun, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Xiao,Liu, Xinrui,Wang, Yan,et al. Exploration of cortical inhibition and habituation in insomnia: Based on CNV and EEG[J]. METHODS,2022,204:73-83. |
APA | Zhang, Xiao.,Liu, Xinrui.,Wang, Yan.,Liu, Chang.,Zhang, Ning.,...&Lv, Yudan.(2022).Exploration of cortical inhibition and habituation in insomnia: Based on CNV and EEG.METHODS,204,73-83. |
MLA | Zhang, Xiao,et al."Exploration of cortical inhibition and habituation in insomnia: Based on CNV and EEG".METHODS 204(2022):73-83. |
入库方式: OAI收割
来源:心理研究所
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