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A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action

文献类型：期刊论文

作者Yuan, Kai17; Zheng, Yong-Bo16,17; Wang, Yi-Jie16; Sun, Yan-Kun17; Gong, Yi-Miao17; Huang, Yue-Tong17; Chen, Xuan15; Liu, Xiao-Xing17; Zhong, Yi16,17; Su, Si-Zhen17
刊名MOLECULAR PSYCHIATRY
出版日期2022-06-06
页码9
ISSN号1359-4184
DOI10.1038/s41380-022-01638-z
通讯作者Kosten, Thomas(kosten@bcm.edu) ; Bao, Yan-Ping(baoyp@bjmu.edu.cn) ; Lu, Lin(linlu@bjmu.edu.cn)
英文摘要Infectious disease epidemics have become more frequent and more complex during the 21(st) century, posing a health threat to the general public and leading to psychological symptoms. The current study was designed to investigate the prevalence of and risk factors associated with depression, anxiety and insomnia symptoms during epidemic outbreaks, including COVID-19. We systematically searched the PubMed, Embase, Web of Science, OVID, Medline, Cochrane databases, bioRxiv and medRxiv to identify studies that reported the prevalence of depression, anxiety or insomnia during infectious disease epidemics, up to August 14(th), 2020. Prevalence of mental symptoms among different populations including the general public, health workers, university students, older adults, infected patients, survivors of infection, and pregnant women across all types of epidemics was pooled. In addition, prevalence of mental symptoms during COVID-19 was estimated by time using meta-regression analysis. A total of 17,506 papers were initially retrieved, and a final of 283 studies met the inclusion criteria, representing a total of 948,882 individuals. The pooled prevalence of depression ranged from 23.1%, 95% confidential intervals (95% CI: [13.9-32.2]) in survivors to 43.3% (95% CI: [27.1-59.6]) in university students, the pooled prevalence of anxiety ranged from 25.0% (95% CI: [12.0-38.0]) in older adults to 43.3% (95% CI: [23.3-63.3]) in pregnant women, and insomnia symptoms ranged from 29.7% (95% CI: [24.4-34.9]) in the general public to 58.4% (95% CI: [28.1-88.6]) in university students. Prevalence of moderate-to-severe mental symptoms was lower but had substantial variation across different populations. The prevalence of mental problems increased over time during the COVID-19 pandemic among the general public, health workers and university students, and decreased among infected patients. Factors associated with increased prevalence for all three mental health symptoms included female sex, and having physical disorders, psychiatric disorders, COVID infection, colleagues or family members infected, experience of frontline work, close contact with infected patients, high exposure risk, quarantine experience and high concern about epidemics. Frequent exercise and good social support were associated with lower risk for these three mental symptoms. In conclusion, mental symptoms are common during epidemics with substantial variation across populations. The population-specific psychological crisis management are needed to decrease the burden of psychological problem and improve the mental wellbeing during epidemic.
收录类别SCI
WOS关键词MENTAL-HEALTH-CARE ; POSTTRAUMATIC-STRESS ; MEDICAL WORKERS ; CHINA ; EPIDEMIC ; SURVIVORS ; OUTBREAK ; IMPACT
资助项目National Key Research and Development Program of China[2021YFC0863700] ; National Key Research and Development Program of China[2019YFA0706200] ; National Key Research and Development Program of China[2019YFC0118502] ; National Natural Science Foundation of China[81761128036] ; National Natural Science Foundation of China[81821092] ; National Natural Science Foundation of China[82171514] ; National Natural Science Foundation of China[82001404] ; National Natural Science Foundation of China[81901345] ; PKU-Baidu Fund[2020BD011]
WOS研究方向Biochemistry & Molecular Biology ; Neurosciences & Neurology ; Psychiatry
语种英语
出版者SPRINGERNATURE
WOS记录号WOS:000806685800004
资助机构National Key Research and Development Program of China ; National Natural Science Foundation of China ; PKU-Baidu Fund
源URL[http://ir.psych.ac.cn/handle/311026/42772]  
专题心理研究所_健康与遗传心理学研究室
通讯作者Kosten, Thomas; Bao, Yan-Ping; Lu, Lin
作者单位1.Peking Univ, Sch Psychol & Cognit Sci, Beijing, Peoples R China
2.Baylor Coll Med, Dept Psychiat Pharmacol Neurosci Immunol, Houston, TX 77030 USA
3.Kings Coll London, Ctr Implementat Sci, Inst Psychiat Psychol & Neurosci, London, England
4.Kings Coll London, Ctr Global Mental Hlth, Inst Psychiat Psychol & Neurosci, London, England
5.Univ Melbourne, Ctr Mental Hlth, Sch Populat & Global Hlth, Global & Cultural Mental Hlth Unit, Melbourne, Vic, Australia
6.Univ Oxford, Dept Psychiat, Oxford, England
7.Harvard Med Sch, Dept Global Hlth & Social Med, Boston, MA USA
8.Univ Washington, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA
9.Capital Med Univ, Beijing Friendship Hosp, Beijing, Peoples R China
10.Peking Univ, Sch Publ Hlth, Beijing, Peoples R China
推荐引用方式
GB/T 7714		 Yuan, Kai,Zheng, Yong-Bo,Wang, Yi-Jie,et al. A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action[J]. MOLECULAR PSYCHIATRY,2022:9.
APA Yuan, Kai.,Zheng, Yong-Bo.,Wang, Yi-Jie.,Sun, Yan-Kun.,Gong, Yi-Miao.,...&Lu, Lin.(2022).A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action.MOLECULAR PSYCHIATRY,9.
MLA Yuan, Kai,et al."A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action".MOLECULAR PSYCHIATRY (2022):9.

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来源：心理研究所

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