Sesquiterpene and Sorbicillinoid Glycosides from the Endophytic Fungus Trichoderma longibrachiatum EN-586 Derived from the Marine Red Alga Laurencia obtusa
文献类型：期刊论文
| 作者 | Wang, Ying1,2,3 ; Li, Xiao-Ming1,3,4; Yang, Sui-Qun1,3,4; Zhang, Fan-Zhong1,2,3; Wang, Bin-Gui1,2,3,4; Li, Hong-Lei1,3,4; Meng, Ling-Hong1,2,3,4
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| 刊名 | MARINE DRUGS
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| 出版日期 | 2022-03-01 |
| 卷号 | 20期号:3页码:11 |
| 关键词 | Trichoderma longibrachiatum sesquiterpene glycoside secondary metabolites antimicrobial activity |
| DOI | 10.3390/md20030177 |
| 通讯作者 | Li, Hong-Lei(lihonglei@qdio.ac.cn) ; Meng, Ling-Hong(m8545303@163.com) |
| 英文摘要 | An unusual sesquiterpene glycoside trichoacorside A (1) and two novel sorbicillinoid glycosides sorbicillisides A (2) and B (3), together with a known compound sorbicillin (4), were isolated and identified from the culture extract of an endophytic fungus Trichoderma longibrachiatum EN-586, obtained from the marine red alga Laurencia obtusa. Trichoacorside A (1) is the first representative of a glucosamine-coupled acorane-type sesquiterpenoid. Their structures were elucidated based on detailed interpretation of NMR and mass spectroscopic data. The absolute configurations were determined by X-ray crystallographic analysis, chemical derivatization, and DP4+ probability analysis. The antimicrobial activities of compounds 1-4 against several human, aquatic, and plant pathogens were evaluated. |
| 资助项目 | National Natural Science Foundation of China[42176115] ; National Natural Science Foundation of China[42006079] ; Qingdao National Laboratory for Marine Science and Technology[YQ2018NO08] ; Qingdao National Laboratory for Marine Science and Technology[OF2019NO03] ; National Natural Science Foundation of Jiangsu province[BK20201211] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000774972100001 |
| 出版者 | MDPI |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/178684]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Li, Hong-Lei; Meng, Ling-Hong |
| 作者单位 | 1.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Peoples R China 2.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, Nanhai Rd 7, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Ying,Li, Xiao-Ming,Yang, Sui-Qun,et al. Sesquiterpene and Sorbicillinoid Glycosides from the Endophytic Fungus Trichoderma longibrachiatum EN-586 Derived from the Marine Red Alga Laurencia obtusa[J]. MARINE DRUGS,2022,20(3):11. |
| APA | Wang, Ying.,Li, Xiao-Ming.,Yang, Sui-Qun.,Zhang, Fan-Zhong.,Wang, Bin-Gui.,...&Meng, Ling-Hong.(2022).Sesquiterpene and Sorbicillinoid Glycosides from the Endophytic Fungus Trichoderma longibrachiatum EN-586 Derived from the Marine Red Alga Laurencia obtusa.MARINE DRUGS,20(3),11. |
| MLA | Wang, Ying,et al."Sesquiterpene and Sorbicillinoid Glycosides from the Endophytic Fungus Trichoderma longibrachiatum EN-586 Derived from the Marine Red Alga Laurencia obtusa".MARINE DRUGS 20.3(2022):11. |
入库方式： OAI收割
来源：海洋研究所
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