Two new sesquiterpenoids from plant endophytic fungus Flammulina velutipes
文献类型：期刊论文
| 作者 | Hu, Jia-Yao3; Yang, Ting3; Liu, Jie3; Xiao, Lei2; Lin, Li-Bin3; Li, Yi-Chao3; Ge, Ming-Yue3; Ji, Ping1; Xiao, Jian3; Wang, Xiao-Ling3 |
| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
 |
| 出版日期 | 2022-05-12 |
| 页码 | 7 |
| 关键词 | Caulophyllum robustum Flammulina velutipes sesquiterpenoid cytotoxicity |
| ISSN号 | 1028-6020 |
| DOI | 10.1080/10286020.2022.2077199 |
| 通讯作者 | Xiao, Jian(xjxs163@126.com) ; Wang, Xiao-Ling(xlwangwang@163.com) |
| 英文摘要 | Two new sesquiterpenoids, flammupin A (1) and flammupin B (2), along with two known compounds, enokipodin C (3) and 5,5'-dibuthoxy-2,2'-bifuran (4) were obtained from Flammulina velutipes, an endophytic fungus isolated from the roots of Caulophyllum robustum Maxim. The structures were elucidated by the combination of HR-ESI-MS, NMR, and ECD analyses. Compound 3 exhibited moderate to potent cytotoxicity against A549, HeLa, and SMMC-7721 cells with IC50 values ranged from 3.69 to 11.84 mu M. |
| WOS关键词 | CUPARENE-TYPE SESQUITERPENES ; INHIBITORY-ACTIVITY ; MYCELIAL CULTURE ; DERIVATIVES ; METABOLITES |
| 资助项目 | National Natural Science Foundation of China[82073727] ; Innovation Capability Support Program of Shaanxi[2018KJXX-044] ; Education Department of Shaanxi Provincial Government[11JS009] |
| WOS研究方向 | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000801930600001 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/301304]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Xiao, Jian; Wang, Xiao-Ling |
| 作者单位 | 1.Chinese Acad Sci, Nat Prod Res Ctr, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China 2.Natl Antidrug Lab Shaanxi Reg Ctr, Qual Control Dept, Xianyang 712000, Peoples R China 3.Baoji Univ Arts & Sci, Coll Chem & Chem Engn, Shaanxi Key Lab Phytochem, Baoji 721013, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Jia-Yao,Yang, Ting,Liu, Jie,et al. Two new sesquiterpenoids from plant endophytic fungus Flammulina velutipes[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2022:7. |
| APA | Hu, Jia-Yao.,Yang, Ting.,Liu, Jie.,Xiao, Lei.,Lin, Li-Bin.,...&Wang, Xiao-Ling.(2022).Two new sesquiterpenoids from plant endophytic fungus Flammulina velutipes.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,7. |
| MLA | Hu, Jia-Yao,et al."Two new sesquiterpenoids from plant endophytic fungus Flammulina velutipes".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2022):7. |
入库方式： OAI收割
来源：上海药物研究所
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