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Prospective Memory Influences Social Functioning in People With First-Episode Schizophrenia: A Network Analysis and Longitudinal Study

文献类型：期刊论文

作者Lui, Simon S. Y.5,6; Zhang, Rui-Ting1,2,3,4; Lau, Wilson Y. S.5; Liu, Amy C. Y.5; Chui, William W. H.5; Wang, Ya3,4; Tsang, Kirby C. M.5; Yeung, Hera K. H.5; Cheung, Eric F. C.5; Chan, Raymond C. K.3,4
刊名JOURNAL OF CLINICAL PSYCHIATRY
出版日期2022-03-01
卷号83期号:2页码:19
ISSN号0160-6689
DOI10.4088/JCP.21m14114
通讯作者Lui, Simon S. Y.(lsy570@hku.hk) ; Chan, Raymond C. K.(rckchan@psych.ac.cn)
英文摘要Background: Prospective memory (PM) impairment is associated with impaired social functioning, but evidence is limited to chronic schizophrenia samples and cross-sectional design.The aim of this study was to utilize network analysis to address the complex interplay between PM, psychopathology, and functional outcome. Methods: This longitudinal study recruited 119 people with first-episode DSM-IV schizophrenia and followed up with them for 2 to 6 years. PM and working memory were assessed at baseline (in 2010-2015) using valid computerized tasks and the Letter-Number Span Test, respectively. Psychopathology and social functioning were assessed at endpoint (in 2016-2017) using the Positive and Negative Syndrome Scale (PANSS) and the Social and Occupational Functioning Assessment Scale (SOFAS), respectively. Network analysis examined the effect of baseline PM on SOFAS while accounting for the effects of psychopathology. Results:The resultant network showed that social functioning, PANSS positive symptoms, and PANSS general symptoms clustered together, whereas time-based and event-based PM and working memory formed another cluster.Time-based PM linked event-based PM and working memory with social functioning. Time-based PM (expected influence [EI] =0.69), event-based PM (EI =0.65), and working memory (EI =0.83) demonstrated high values of expected influence, but social functioning (variance explained =0.685) and PANSS negative (variance explained =0.657) and general (variance explained =0.583) subscales demonstrated high values of predictability. Conclusions: Time-based PM is the central node linking neurocognitive functions with social functioning. PM and working memory are "target" nodes for interventions bringing changes to the network, whereas social functioning and psychopathology are "malleable" nodes. PM and working memory are promising intervention targets for functional recovery in schizophrenia.
收录类别SCI
WOS关键词RATING-SCALE ; DEPRESSION SCALE ; INDIVIDUALS ; ASSOCIATION ; IMPAIRMENTS ; SYMPTOMS ; PREDICTS ; SKILLS
资助项目CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences ; Phillip K. H. Wong Foundation
WOS研究方向Psychology ; Psychiatry
语种英语
出版者PHYSICIANS POSTGRADUATE PRESS
WOS记录号WOS:000830047400013
资助机构CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences ; Phillip K. H. Wong Foundation
源URL[http://ir.psych.ac.cn/handle/311026/43024]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Lui, Simon S. Y.; Chan, Raymond C. K.
作者单位1.Hunan Normal Univ, Cognit & Human Behav Key Lab Hunan Prov, Changsha, Peoples R China
2.Hunan Normal Univ, Sch Educ Sci, Dept Psychol, Changsha, Peoples R China
3.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
4.Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Beijing, Peoples R China
5.Castle Peak Hosp, Hong Kong, Peoples R China
6.Univ Hong Kong, Dept Psychiat, Hong Kong, Peoples R China
推荐引用方式
GB/T 7714		 Lui, Simon S. Y.,Zhang, Rui-Ting,Lau, Wilson Y. S.,et al. Prospective Memory Influences Social Functioning in People With First-Episode Schizophrenia: A Network Analysis and Longitudinal Study[J]. JOURNAL OF CLINICAL PSYCHIATRY,2022,83(2):19.
APA Lui, Simon S. Y..,Zhang, Rui-Ting.,Lau, Wilson Y. S..,Liu, Amy C. Y..,Chui, William W. H..,...&Chan, Raymond C. K..(2022).Prospective Memory Influences Social Functioning in People With First-Episode Schizophrenia: A Network Analysis and Longitudinal Study.JOURNAL OF CLINICAL PSYCHIATRY,83(2),19.
MLA Lui, Simon S. Y.,et al."Prospective Memory Influences Social Functioning in People With First-Episode Schizophrenia: A Network Analysis and Longitudinal Study".JOURNAL OF CLINICAL PSYCHIATRY 83.2(2022):19.

入库方式： OAI收割

来源：心理研究所

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