Cyclic poly(beta-amino ester)s with enhanced gene transfection activity synthesized through intra-molecular cyclization
文献类型：期刊论文
| 作者 | Wang, Chenfei1; Huang, Xiaobei2; Sun, Litao1; Li, Qiuxia1; Li, Zhili1; Yong, Haiyang1; Che, Delu3; Yan, Cong3; Geng, Songmei3; Wang, Wenxin4 |
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2022-01-12 |
| 页码 | 4 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/d1cc06480k |
| 通讯作者 | Geng, Songmei(gsm312@yahoo.com) ; Zhou, Dezhong(dezhong.zhou@xjtu.edu.cn) |
| 英文摘要 | Topological structure plays a critical role in gene delivery of cationic polymers. Cyclic poly(beta-amino ester)s (CPAEs) are successfully synthesized via sequential Michael addition and free radical initiating ring-closure reaction. The CPAEs exhibit superior gene transfection efficiency and safety profile compared to their linear counterparts. |
| 资助项目 | National Natural Science Foundation of China (NSFC)[51903202] ; National Natural Science Foundation of China (NSFC)[51873179] ; Key R&D Program of Shaanxi Province[2020GXLH-Y-016] ; Natural Science Foundation of Shaanxi Province[2020JM-055] ; Fundamental Research Funds for the Central Universities[xtr042019020] ; Young Talents Support Plan of Xi'an Jiaotong University[HG6J002] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000743619000001 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/14880]  |
| 专题 | 中国科学院重庆绿色智能技术研究院 |
| 通讯作者 | Geng, Songmei; Zhou, Dezhong |
| 作者单位 | 1.Xi An Jiao Tong Univ, Sch Chem Engn & Technol, Xian 710049, Peoples R China 2.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China 3.Xi An Jiao Tong Univ, Hosp 2, Dept Dermatol, Xian 710061, Peoples R China 4.Univ Coll Dublin, Charles Inst Dermatol, Sch Med, Dublin 4, Ireland |
| 推荐引用方式 GB/T 7714 | Wang, Chenfei,Huang, Xiaobei,Sun, Litao,et al. Cyclic poly(beta-amino ester)s with enhanced gene transfection activity synthesized through intra-molecular cyclization[J]. CHEMICAL COMMUNICATIONS,2022:4. |
| APA | Wang, Chenfei.,Huang, Xiaobei.,Sun, Litao.,Li, Qiuxia.,Li, Zhili.,...&Zhou, Dezhong.(2022).Cyclic poly(beta-amino ester)s with enhanced gene transfection activity synthesized through intra-molecular cyclization.CHEMICAL COMMUNICATIONS,4. |
| MLA | Wang, Chenfei,et al."Cyclic poly(beta-amino ester)s with enhanced gene transfection activity synthesized through intra-molecular cyclization".CHEMICAL COMMUNICATIONS (2022):4. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
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