Yeast powder derived carbon quantum dots for dopamine detection and living cell imaging
文献类型：期刊论文
| 作者 | Cao, Xue2; Shao, Congying2; Zhang, Cheng2; Liang, Mengna2; Wang, Yongxiang2; Cheng, Jun1 ; Lu, Shun3
|
| 刊名 | ANALYTICAL METHODS
 |
| 出版日期 | 2022-03-31 |
| 卷号 | 14期号:13页码:1342-1350 |
| ISSN号 | 1759-9660 |
| DOI | 10.1039/d2ay00231k |
| 通讯作者 | Shao, Congying(shaocongying@163.com) ; Lu, Shun(ysfield@live.com) |
| 英文摘要 | Dopamine (DA) is an important neurotransmitter in the brain of mammals. There is a critical need for fast and sensitive determination approaches to monitor these potential diseases due to various weaknesses in clinical trials of the existing methods for DA detection. DA can effectively quench the fluorescence of carbon quantum dots (CDs) through the inner filter effect and static quenching. In this work, fluorescent yeast CDs (Y-CDs) were prepared via a simple hydrothermal approach of using yeast powder and regarded as the fluorescent nanoprobe to directly monitor the DA concentration. The as-prepared detection platform exhibited excellent sensitivity and selectivity toward DA with a low detection limit of 30 nM and a wide linear range of 0.05-150 mu M. Benefiting from these outstanding features, the developed label-free method has been successfully applied for fast DA detection in human serum samples with satisfactory recoveries. Furthermore, it demonstrated that the Y-CDs were well suitable for live cell imaging and showed low toxicity toward MCF-7 cells. Consequently, this work will facilitate the great potential of the versatile Y-CDs in developing biosensors for clinical diagnosis and other biological applications. |
| 资助项目 | Natural Science Foundation of Anhui Provincial Department of Education[KJ2019A0598] ; Natural Science Foundation of Anhui Province[1708085QB44] ; Excellent Young Talents Fund Program of Higher Education Institutions of Anhui Province[gxyq2019168] |
| WOS研究方向 | Chemistry ; Food Science & Technology ; Spectroscopy |
| 语种 | 英语 |
| WOS记录号 | WOS:000770037600001 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.138/handle/2HOD01W0/15378]  |
| 专题 | 中国科学院重庆绿色智能技术研究院 |
| 通讯作者 | Shao, Congying; Lu, Shun |
| 作者单位 | 1.Chongqing Jiaotong Univ, Sch Mechatron & Vehicle Engn, Chongqing 400074, Peoples R China 2.Huaibei Normal Univ, Coll Chem & Mat Sci, Key Lab Green & Precise Synthet Chem, Minist Educ, Huaibei 235000, Anhui, Peoples R China 3.Chinese Acad Sci, Chongqing Inst Green & Intelligent Technol, Chongqing 400714, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cao, Xue,Shao, Congying,Zhang, Cheng,et al. Yeast powder derived carbon quantum dots for dopamine detection and living cell imaging[J]. ANALYTICAL METHODS,2022,14(13):1342-1350. |
| APA | Cao, Xue.,Shao, Congying.,Zhang, Cheng.,Liang, Mengna.,Wang, Yongxiang.,...&Lu, Shun.(2022).Yeast powder derived carbon quantum dots for dopamine detection and living cell imaging.ANALYTICAL METHODS,14(13),1342-1350. |
| MLA | Cao, Xue,et al."Yeast powder derived carbon quantum dots for dopamine detection and living cell imaging".ANALYTICAL METHODS 14.13(2022):1342-1350. |
入库方式： OAI收割
来源：重庆绿色智能技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。