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Association of empathy with clinical symptoms and cognitive function in Chinese chronic schizophrenia patients with and without deficit syndrome

文献类型：期刊论文

作者Liu, Junyao1,2; Tian, Yang1,2; Wei, Shuochi1,2; Wang, Wenjia1,2; Wang, Dongmei1,2; Zhou, Huixia1,2; Zhang, Xiang-Yang1,2
刊名PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
出版日期2022-12-20
卷号119页码:7
关键词Schizophrenia Deficit syndrome Neurocognition Empathy
ISSN号0278-5846
DOI10.1016/j.pnpbp.2022.110592
通讯作者Zhang, Xiang-Yang(zhangxy@psych.ac.cn)
英文摘要Background: Patients with deficit syndrome (DS) are known to experience cognitive impairment. However, there is no consistent conclusion on the impairment of neurocognitive features in DS patients, and no studies have examined their empathy. The purpose of this study was to compare neurocognition and empathy in patients with DS and non-DS schizophrenia. Methods: Totally, 665 patients with chronic schizophrenia were enrolled. DS patients were identified by the Proxy Scale for Deficit Syndrome (PDS). Neurocognition and social cognition were assessed by Repeatable Battery for the measurement of Neuropsychological Status (RBANS) and the Interpersonal Reactivity Index (IRI), respectively. In addition, psychopathological symptom severity was assessed by the Positive and Negative Syndrome Scale (PANSS). Results: Participants included 150 patients with DS and 140 patients with non-DS. DS patients performed significantly worse on the all RBANS domain (except for visuospatial) and total scores as well as IRI scores. Regression analysis showed that PANSS general psychopathology and education were associated with RBANS total score in the DS group (adjusted R-2 = 0.29), while education and PANSS negative symptoms were correlated with RBANS total score in non-DS patients (adjusted R-2 = 0.33). In the non-DS group, suicide attempts and PANSS negative symptom score were independently associated with IRI total score (adjusted R-2 = 0.06), whereas in the DS group, no variable was associated with IRI total score. Conclusions: Our findings suggest that patients with DS may have poor neumcognitive and empathy performance. In chronic schizophrenia patients, negative symptoms may play a different role in cognition between DS and non-DS groups.
收录类别SCI
WOS关键词DIRECT-CURRENT STIMULATION ; SELF-REPORTED EMPATHY ; NEGATIVE SYMPTOMS ; EMOTIONAL EMPATHY ; HETEROGENEITY ; METAANALYSIS
资助项目CAS International Coopera-tion Research Program[153111KYSB20190004] ; CAS Pioneer Hundred Talents Program ; CAS Key Lab of Mental Health
WOS研究方向Neurosciences & Neurology ; Pharmacology & Pharmacy ; Psychiatry
语种英语
WOS记录号WOS:000832796000004
出版者PERGAMON-ELSEVIER SCIENCE LTD
资助机构CAS International Coopera-tion Research Program ; CAS Pioneer Hundred Talents Program ; CAS Key Lab of Mental Health
源URL[http://ir.psych.ac.cn/handle/311026/43051]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Zhang, Xiang-Yang
作者单位1.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Beijing, Peoples R China
推荐引用方式
GB/T 7714		 Liu, Junyao,Tian, Yang,Wei, Shuochi,et al. Association of empathy with clinical symptoms and cognitive function in Chinese chronic schizophrenia patients with and without deficit syndrome[J]. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY,2022,119:7.
APA Liu, Junyao.,Tian, Yang.,Wei, Shuochi.,Wang, Wenjia.,Wang, Dongmei.,...&Zhang, Xiang-Yang.(2022).Association of empathy with clinical symptoms and cognitive function in Chinese chronic schizophrenia patients with and without deficit syndrome.PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY,119,7.
MLA Liu, Junyao,et al."Association of empathy with clinical symptoms and cognitive function in Chinese chronic schizophrenia patients with and without deficit syndrome".PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY 119(2022):7.

入库方式： OAI收割

来源：心理研究所

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