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Disruption of Functional Brain Networks Underlies the Handwriting Deficit in Children With Developmental Dyslexia

文献类型：期刊论文

作者Liu, Zhengyan2,3; Li, Junjun2,3; Bi, Hong-Yan2,3; Xu, Min1; Yang, Yang2,3
刊名FRONTIERS IN NEUROSCIENCE
出版日期2022-07-18
卷号16页码:12
关键词developmental dyslexia handwriting fMRI functional brain network children
DOI10.3389/fnins.2022.919440
通讯作者Xu, Min(xumin@szu.edu.cn) ; Yang, Yang(yangyang@psych.ac.cn)
英文摘要Developmental dyslexia (DD) is a neurological-based learning disorder that affects 5-17.5% of children. Handwriting difficulty is a prevailing symptom of dyslexia, but its neural mechanisms remain elusive. Using functional magnetic resonance imaging (fMRI), this study examined functional brain networks associated with handwriting in a copying task in Chinese children with DD (n = 17) and age-matched children (n = 36) . We found that dyslexics showed reduced network connectivity between the sensory-motor network (SMN) and the visual network (VN), and between the default mode network (DMN) and the ventral attention network (VAN) during handwriting, but not during drawing geometric figures. Moreover, the connectivity strength of the networks showing group differences was correlated with handwriting speed, reading and working memory, suggesting that the handwriting deficit in DD is linked with disruption of a large-scale brain network supporting motoric, linguistic and executive control processes. Taken together, this study demonstrates the alternations of functional brain networks that underly the handwriting deficit in Chinese dyslexia, providing a new clue for the neural basis of DD.
收录类别SCI
WOS关键词DEFAULT MODE ; WHOLE-BRAIN ; CONNECTIVITY ; CHINESE ; METAANALYSIS ; LANGUAGE ; MOTOR ; REPRESENTATIONS ; ASSOCIATION ; ACTIVATION
WOS研究方向Neurosciences & Neurology
语种英语
出版者FRONTIERS MEDIA SA
WOS记录号WOS:000834485500001
源URL[http://ir.psych.ac.cn/handle/311026/43054]  
专题心理研究所_中国科学院行为科学重点实验室
通讯作者Xu, Min; Yang, Yang
作者单位1.Shenzhen Univ, Ctr Brain Disorders & Cognit Sci, Sch Psychol, Shenzhen, Peoples R China
2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
3.Chinese Acad Sci, Inst Psychol, Ctr Brain Sci & Learning Difficulties, CAS Key Lab Behav Sci, Beijing, Peoples R China
推荐引用方式
GB/T 7714		 Liu, Zhengyan,Li, Junjun,Bi, Hong-Yan,et al. Disruption of Functional Brain Networks Underlies the Handwriting Deficit in Children With Developmental Dyslexia[J]. FRONTIERS IN NEUROSCIENCE,2022,16:12.
APA Liu, Zhengyan,Li, Junjun,Bi, Hong-Yan,Xu, Min,&Yang, Yang.(2022).Disruption of Functional Brain Networks Underlies the Handwriting Deficit in Children With Developmental Dyslexia.FRONTIERS IN NEUROSCIENCE,16,12.
MLA Liu, Zhengyan,et al."Disruption of Functional Brain Networks Underlies the Handwriting Deficit in Children With Developmental Dyslexia".FRONTIERS IN NEUROSCIENCE 16(2022):12.

入库方式： OAI收割

来源：心理研究所

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