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Seven diastereomeric aucubigenin derivatives from Pseudolysimachion linariifolium subsp. dilatatum

文献类型：期刊论文

作者Xue, Hai-Bing3; Wang, Peng3; Wu, Longlong3; Qian, Fei2; Chen, Kai-Xian1,3; Zhang, Liu-Qiang3; Li, Yi-Ming3
刊名JOURNAL OF MOLECULAR STRUCTURE
出版日期2022-09-05
卷号1263期号:1页码:7
ISSN号0022-2860
关键词Pseudolysimachion linariifolium subsp. dilatatum Iridoids Linariifolum L-Q Diastereomer
DOI10.1016/j.molstruc.2022.133303
通讯作者Zhang, Liu-Qiang(lqzhang@shutcm.edu.cn) ; Li, Yi-Ming(ymli@shutcm.edu.cn)
英文摘要Eight new iridoids, linariifolums L-R (1-7) and linariifolioside B (8), along with four known iridoid compounds were obtained from Pseudolysimachion linariifolium subsp. dilatatum, where compounds 1-6 were diastereomers. Their structures were elucidated based on 1D and 2D NMR and ESIMS analysis; absolute configurations were determined by ECD calculations. The nitric oxide inhibitory activity of all compounds was evaluated in the LPS-stimulated RAW264.7 cells; however, no inhibitory effect was discovered. (C) 2022 Elsevier B.V. All rights reserved.
WOS关键词CONSTITUENTS
资助项目National Natural Science Foundation of China[81973458] ; Shanghai Sailing Program[19YF1449100] ; Opening Foundation of National Facility for Translational Medicinal (Shanghai)[TMSK-2021-404] ; program of Shanghai E-research Institute of Bioactive Constituents in Traditional Chinese Medicine
WOS研究方向Chemistry
语种英语
出版者ELSEVIER
WOS记录号WOS:000832838200013
源URL[http://119.78.100.183/handle/2S10ELR8/301899]  
专题中国科学院上海药物研究所
通讯作者Zhang, Liu-Qiang; Li, Yi-Ming
作者单位1.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
2.Shanghai Univ Tradit Chinese Med, Inst Interdisciplinary Med Sci, Shanghai 201203, Peoples R China
3.Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714		 Xue, Hai-Bing,Wang, Peng,Wu, Longlong,et al. Seven diastereomeric aucubigenin derivatives from Pseudolysimachion linariifolium subsp. dilatatum[J]. JOURNAL OF MOLECULAR STRUCTURE,2022,1263(1):7.
APA Xue, Hai-Bing.,Wang, Peng.,Wu, Longlong.,Qian, Fei.,Chen, Kai-Xian.,...&Li, Yi-Ming.(2022).Seven diastereomeric aucubigenin derivatives from Pseudolysimachion linariifolium subsp. dilatatum.JOURNAL OF MOLECULAR STRUCTURE,1263(1),7.
MLA Xue, Hai-Bing,et al."Seven diastereomeric aucubigenin derivatives from Pseudolysimachion linariifolium subsp. dilatatum".JOURNAL OF MOLECULAR STRUCTURE 1263.1(2022):7.

入库方式： OAI收割

来源：上海药物研究所

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