Bayexer: an accurate and fast Bayesian demultiplexer for Illumina sequences
文献类型：期刊论文
| 作者 | Yi, Haisi1; Li, Zhe4; Li, Tao; Zhao, Jindong3 |
| 刊名 | BIOINFORMATICS
 |
| 出版日期 | 2015 |
| 卷号 | 31期号:24页码:4000-4002 |
| ISSN号 | 1367-4803 |
| DOI | 10.1093/bioinformatics/btv501 |
| 文献子类 | Article |
| 英文摘要 | Demultiplexing is used after high-throughput sequencing to in silico assign reads to the samples of origin based on the sequenced reads of the indices. Existing demultiplexing tools based on the similarity between the read index and the reference index sequences may fail to provide satisfactory results on low-quality datasets. We developed Bayexer, a Bayesian demultiplexing algorithm for Illumina sequencers. Bayexer uses the information extracted directly from the contaminant sequences of the targeting reads as the training dataset for a naive Bayes classifier to assign reads. According to our evaluation, Bayexer provides higher capability, accuracy and speed on various real datasets than other tools. |
| 学科主题 | Biochemical Research Methods ; Biotechnology & Applied Microbiology ; Computer Science, Interdisciplinary Applications ; Mathematical & Computational Biology ; Statistics & Probability |
| 出版地 | OXFORD |
| 电子版国际标准刊号 | 1460-2059 |
| WOS研究方向 | Science Citation Index Expanded (SCI-EXPANDED) |
| 语种 | 英语 |
| WOS记录号 | WOS:000366630400019 |
| 出版者 | OXFORD UNIV PRESS |
| 资助机构 | Autonomous Projects of the State Key Laboratory of Freshwater Ecology and Biotechnology [2011FBZ31, 2011FBZ32] |
| 源URL | [http://ir.ibcas.ac.cn/handle/2S10CLM1/25798]  |
| 专题 | 植物研究所_系统与进化植物学研究中心_系统与进化植物学研究中心_学位论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, Key Lab Algal Biol, Wuhan 430072, Hubei, Peoples R China 2.Peking Univ, Coll Life Sci, Beijing 100871, Peoples R China 3.Chinese Acad Sci, Inst Bot, State Key Lab Systemat & Evolutionary, Beijing 100093, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yi, Haisi,Li, Zhe,Li, Tao,et al. Bayexer: an accurate and fast Bayesian demultiplexer for Illumina sequences[J]. BIOINFORMATICS,2015,31(24):4000-4002. |
| APA | Yi, Haisi,Li, Zhe,Li, Tao,&Zhao, Jindong.(2015).Bayexer: an accurate and fast Bayesian demultiplexer for Illumina sequences.BIOINFORMATICS,31(24),4000-4002. |
| MLA | Yi, Haisi,et al."Bayexer: an accurate and fast Bayesian demultiplexer for Illumina sequences".BIOINFORMATICS 31.24(2015):4000-4002. |
入库方式： OAI收割
来源：植物研究所
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