中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Longitudinal Structural MRI Data Prediction in Nondemented and Demented Older Adults via Generative Adversarial Convolutional Network

文献类型:期刊论文

作者Song, Liyao2; Wang, Quan1; Li, Haiwei1; Fan, Jiancun2; Hu, Bingliang1
刊名NEURAL PROCESSING LETTERS
关键词Structural MRI Longitudinal prediction GAN Nondemented and demented older adults
ISSN号1370-4621;1573-773X
DOI10.1007/s11063-022-10922-6
产权排序2
英文摘要

Alzheimer's disease (AD) is the most common cause of dementia and threatens the health of millions of people. Early stage diagnosis of AD is critical for improving clinical outcomes and longitudinal magnetic resonance imaging (MRI) data collection can be used to monitor the progress of each patient. However, missing data is a common problem in longitudinal AD studies. The main factors come from subject dropouts and failed scans. This hinders the acquisition of longitudinal sequences that consist of multi-time-point magnetic resonance (MR) images at relatively uniform intervals. In this paper, we present a generative adversarial convolutional network to predict missing structural MRI data. In particular, we include multiple MRI scans as a temporal sequence collected at different times and determine the spatio-temporal relationship between the different scans in the proposed network. We adopt residual bottlenecks in the generator to decrease parameter values and deepen the network. In order to make full use of the longitudinal information, our discriminator classifies not only real MR images from generated MR images, but also fake sequences from real sequences in which the longitudinal MR images for all time points come from the dataset, only the last MR image comes from the generator. Results of our experiment show that our method performs more accurately for the longitudinal structural MRI data prediction of a brain afflicted with AD.

语种英语
WOS记录号WOS:000835611900002
出版者SPRINGER
源URL[http://ir.opt.ac.cn/handle/181661/96108]  
专题西安光学精密机械研究所_光学影像学习与分析中心
通讯作者Wang, Quan; Li, Haiwei; Fan, Jiancun
作者单位1.Chinese Acad Sci, Key Lab Spectral Imaging Technol, Xian Inst Opt & Precis Mech, Xian, Peoples R China
2.Xi An Jiao Tong Univ, Sch Informat & Commun Engn, Xian, Peoples R China
推荐引用方式
GB/T 7714
Song, Liyao,Wang, Quan,Li, Haiwei,et al. Longitudinal Structural MRI Data Prediction in Nondemented and Demented Older Adults via Generative Adversarial Convolutional Network[J]. NEURAL PROCESSING LETTERS.
APA Song, Liyao,Wang, Quan,Li, Haiwei,Fan, Jiancun,&Hu, Bingliang.
MLA Song, Liyao,et al."Longitudinal Structural MRI Data Prediction in Nondemented and Demented Older Adults via Generative Adversarial Convolutional Network".NEURAL PROCESSING LETTERS

入库方式: OAI收割

来源:西安光学精密机械研究所

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