Mixed Metal Metal-Organic Frameworks Derived Carbon Supporting ZnFe2O4/C for High-Performance Magnetic Particle Imaging
文献类型：期刊论文
| 作者 | Jiang, Zhenqi; Han, Xiao; Du, Yang; Li, Yanying; Li, Yong; Li, Juan; Tian, Jie; Wu, Aiguo |
| 刊名 | NANO LETTERS
 |
| 出版日期 | 2021 |
| 卷号 | 21期号:7页码:2730-2737 |
| 关键词 | FAVORABLE BIOCOMPATIBILITY NANOPARTICLES ACCUMULATION |
| 英文摘要 | Recently, magnetic particle imaging (MPI) has shown diverse biomedical applications such as cell tracking, lung perfusion, image-guided hyperthermia, and so forth. However, the currently reported MPI agents cannot achieve the possible theoretical detection limit of MPI (20 nM). A previous theoretical study has shown that the MPI performance of superparamagnetic iron oxide nanoparticles (SPIONs) can be enhanced by carbon supporting and metal doping. In the current study, a series of mixed metal metal-organic framework-derived carbon supporting SPIONs were synthesized by pyrolysis. Among the synthesized SPIONs, the MPI signal intensity of ZnFe2O4/C@PDA was found to be 4.7 times higher than the commercial MPI contrast (Vivotrax) having the same Fe concentration. ZnFe2O4/C@PDA also showed the highest MPI intensity in tumor-bearing-mice among all tested samples. Furthermore, they were found highly biocompatible and showed linear cell quantification. This work can open new avenues for the design and development of novel and high-performance MPI agents. |
| 源URL | [http://ir.nimte.ac.cn/handle/174433/22025]  |
| 专题 | 中国科学院宁波材料技术与工程研究所 2021专题_期刊论文 |
| 作者单位 | 1.Li, J 2.Wu, AG (corresponding author), Chinese Acad Sci, Zhejiang Engn Res Ctr Biomed Mat, Cixi Inst Biomed Engn, Ningbo Inst Mat Technol & Engn,CAS Key Lab Magnet, Ningbo 315201, Peoples R China. 3.Tian, J (corresponding author), Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, State Key Lab Management & Control Complex Syst, Beijing 100190, Peoples R China. 4.Wu, AG (corresponding author), Adv Energy Sci & Technol Guangdong Lab, Huizhou 516003, Peoples R China. 5.Tian, J (corresponding author), Beihang Univ, Beijing Adv Innovat Ctr Big Data Based Precis Med, Sch Med, Beijing 100191, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Jiang, Zhenqi,Han, Xiao,Du, Yang,et al. Mixed Metal Metal-Organic Frameworks Derived Carbon Supporting ZnFe2O4/C for High-Performance Magnetic Particle Imaging[J]. NANO LETTERS,2021,21(7):2730-2737. |
| APA | Jiang, Zhenqi.,Han, Xiao.,Du, Yang.,Li, Yanying.,Li, Yong.,...&Wu, Aiguo.(2021).Mixed Metal Metal-Organic Frameworks Derived Carbon Supporting ZnFe2O4/C for High-Performance Magnetic Particle Imaging.NANO LETTERS,21(7),2730-2737. |
| MLA | Jiang, Zhenqi,et al."Mixed Metal Metal-Organic Frameworks Derived Carbon Supporting ZnFe2O4/C for High-Performance Magnetic Particle Imaging".NANO LETTERS 21.7(2021):2730-2737. |
入库方式： OAI收割
来源：宁波材料技术与工程研究所
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