Laser-Mediated antibacterial effects of Few- and Multi-Layer Ti3C2Tx MXenes
文献类型：期刊论文
| 作者 | Rosenkranz, Andreas; Perini, Giordano; Aguilar-Hurtado, Jose Y.; Zambrano, Dario F.; Wang, Bo; Niccolini, Benedetta; Henriques, Patricia C.; Rosa, Enrico; De Maio, Flavio; Delogu, Giovanni |
| 刊名 | APPLIED SURFACE SCIENCE
 |
| 出版日期 | 2021 |
| 卷号 | 567 |
| 关键词 | RAY PHOTOELECTRON-SPECTROSCOPY NANOSHEETS |
| 英文摘要 | Ti3C2Tx nano-sheets (MXenes) with excellent light-conversion capacity have gained importance in treating infectious diseases due to their limited bacterial resistance. In this study, we exploit this property to design photothermal antibacterial therapy using few- (FX) and multi-layer (MX) Ti3C2Tx nano-sheets. We demonstrate that FX have a higher cytocompatibility and conversion of light to heat, but MX show a better efficacy in inhibiting growth of S. aureus and E. coli due to MXenes' reversible bacteria trapping. For MX (25 mu g/mL), square 37% of E. coli and square 23% of S. aureus cells survived, while the effect was less pronounced for FX with square 72% of E. coli and square 46% of S. aureus viable cells after treatment. After using 100 mu g/mL of MX, square 11% of E. coli and square 46% of S. aureus survived, while FX had only a mild effect on both species. The NIR laser treatment increased the efficacy of both materials: 100 mu g/mL of MX combined with 5 min laser treatment at 5.7 W cm(-2) completely killed both species. For FX, the treatment with 3 W cm(-2) and the highest concentration (100 mu g/mL) induced an effect comparable to MX (87% on E. coli, 95% on S.aureus). The combined NIR MXene treatment causes an irreversible cell death linked to the loss of cell integrity (DNA release quantification and bacteria debris observation). |
| 源URL | [http://ir.nimte.ac.cn/handle/174433/21294]  |
| 专题 | 2021专题_期刊论文 |
| 作者单位 | 1.Palmieri, V (corresponding author), Fdn Policlin Univ A Gemelli IRCSS, I-00168 Rome, Italy. 2.Palmieri, V (corresponding author), Univ Cattolica Sacro Cuore, Dipartimento Neurosci, Largo Francesco Vito 1, I-00168 Rome, Italy. 3.Palmieri, V (corresponding author), CNR, Ist Sistemi Complessi, Via Taurini 19, I-00185 Rome, Italy. |
| 推荐引用方式 GB/T 7714 | Rosenkranz, Andreas,Perini, Giordano,Aguilar-Hurtado, Jose Y.,et al. Laser-Mediated antibacterial effects of Few- and Multi-Layer Ti3C2Tx MXenes[J]. APPLIED SURFACE SCIENCE,2021,567. |
| APA | Rosenkranz, Andreas.,Perini, Giordano.,Aguilar-Hurtado, Jose Y..,Zambrano, Dario F..,Wang, Bo.,...&Papi, Massimiliano.(2021).Laser-Mediated antibacterial effects of Few- and Multi-Layer Ti3C2Tx MXenes.APPLIED SURFACE SCIENCE,567. |
| MLA | Rosenkranz, Andreas,et al."Laser-Mediated antibacterial effects of Few- and Multi-Layer Ti3C2Tx MXenes".APPLIED SURFACE SCIENCE 567(2021). |
入库方式： OAI收割
来源：宁波材料技术与工程研究所
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