Alginate/gelatin mineralized hydrogel modified by multilayers electrospun membrane of cellulose: Preparation, properties and in-vitro degradation
文献类型：期刊论文
| 作者 | Jing, Yidan; Mahmud, Sakil; Wu, Chenfeng; Zhang, Xiaomin; Su, Shengpei; Zhu, Jin |
| 刊名 | POLYMER DEGRADATION AND STABILITY
 |
| 出版日期 | 2021 |
| 卷号 | 192 |
| 关键词 | SCAFFOLDS |
| 英文摘要 | Sodium alginate (SA) hydrogel has a broad prospect in tissue engineering and other biomedical fields due to its biocompatibility. However, the single SA hydrogel has shown poor mechanical properties and cell adhesion, which seriously limited its application and development in tissue engineering scaffolds. Herein, the SA/gelatin (SAG) hydrogel was modified by the multilayers electrospinning membrane of cellulose (SAG-C). It showed excellent mechanical properties when the layer number of electrospinning membrane got to three. After mineralization (M-SAG-C), the mechanical and biocompatible properties have been further improved. The SAG, SAG-C, and M-SAG-C series hydrogels all had good water retention, swelling rates, and good degradation performance. The fluorescence staining and cell proliferation experiments showed that M-SAG, SAG-C, and M-SAG-C hydrogel materials had no apparent cytotoxicity. Simultaneously, the introduction of bone-like apatite in the M-SAG-C hydrogel material allowed the cells to have better adhesion and proliferation ability on the composite surface. And the higher the degree of mineralization, the better the cell compatibility of the hydrogel material. Therefore, such hydrogels had excellent biocompatibility and mechanical properties, which could be widely used in tissue engineering. (C) 2021 Elsevier Ltd. All rights reserved. |
| 源URL | [http://ir.nimte.ac.cn/handle/174433/21432]  |
| 专题 | 2021专题_期刊论文 |
| 作者单位 | 1.Zhang, XM (corresponding author), Hunan Normal Univ, Natl & Local Joint Engn Lab New Petrochem Mat & F, Changsha 410081, Peoples R China. 2.Zhang, XM (corresponding author), Hunan Normal Univ, Minist Educ China, Key Lab Chem Biol & Tradit Chinese Med Res, Changsha 410081, Peoples R China. 3.Zhang, XM (corresponding author), Hunan Normal Univ, Key Lab Fine Proc Resources & Adv Mat Hunan Prov, Changsha 410081, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Jing, Yidan,Mahmud, Sakil,Wu, Chenfeng,et al. Alginate/gelatin mineralized hydrogel modified by multilayers electrospun membrane of cellulose: Preparation, properties and in-vitro degradation[J]. POLYMER DEGRADATION AND STABILITY,2021,192. |
| APA | Jing, Yidan,Mahmud, Sakil,Wu, Chenfeng,Zhang, Xiaomin,Su, Shengpei,&Zhu, Jin.(2021).Alginate/gelatin mineralized hydrogel modified by multilayers electrospun membrane of cellulose: Preparation, properties and in-vitro degradation.POLYMER DEGRADATION AND STABILITY,192. |
| MLA | Jing, Yidan,et al."Alginate/gelatin mineralized hydrogel modified by multilayers electrospun membrane of cellulose: Preparation, properties and in-vitro degradation".POLYMER DEGRADATION AND STABILITY 192(2021). |
入库方式： OAI收割
来源：宁波材料技术与工程研究所
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