Overview of the preparation method, structure and function, and application of natural peptides and polypeptides
文献类型：期刊论文
| 作者 | Feng, Li6; Wang, Yue5; Yang, Jian2; Sun, Yi-fan1; Li, Yi-wei5; Ye, Zi-hong5; Lin, Han-bin3,4; Yang, Ke4,5 |
| 刊名 | BIOMEDICINE & PHARMACOTHERAPY
 |
| 出版日期 | 2022-09-01 |
| 卷号 | 153页码:7 |
| 关键词 | Natural peptide and polypeptide Preparation Structure-activity relationship Application |
| ISSN号 | 0753-3322 |
| DOI | 10.1016/j.biopha.2022.113493 |
| 通讯作者 | Lin, Han-bin(linhanbin@simm.ac.cn) ; Yang, Ke(yangyongyao168@sina.com) |
| 英文摘要 | Natural polypeptides, a kind of molecular polymer with obvious biological activity, are widely existing in nature. They participate in various physiological activities of living organisms and play an important role in promoting human health. They are also widely applied in medicine, food, and cosmetic industries. By searching literature from Pubmed, Google Scholar, Web of Science, Springer Link and Elsevier, this work presents an overview of the preparation methods, the relationship between structure and function, and the application of natural poly -peptides. The preparation methods mainly include solvent extraction, enzymatic decomposition, microbiological fermentation, chemical synthesis, genetic engineering recombination, and using cell free system. Natural poly-peptide's physiological function mainly includes antioxidative, antibacterial, antihypertensive. This review could provide scientific basis for the research and development of natural polypeptide. |
| WOS关键词 | ANGIOTENSIN-CONVERTING ENZYME ; ACE INHIBITORY PEPTIDES ; AMINO-ACID-SEQUENCE ; ANTIMICROBIAL PEPTIDE ; IN-VITRO ; ANTIBACTERIAL PEPTIDES ; ANTIOXIDANT ACTIVITY ; RICH PEPTIDE ; PROTEINS ; MECHANISM |
| 资助项目 | National Natural Science Founda-tion of China[81803761] ; National Natural Science Founda-tion of China[82100391] ; China Postdoctoral Science Foundation[2019M652144] ; China Postdoctoral Science Foundation[2060302] ; High-level new R&D institute of Department of Science and Technology of Guangdong Province[2019B090904008] ; High-level Innovative Research Institute of Department of Science and Technology of Guang-dong Province[2021B0909050003] ; Shandong Provincial Key Research and Development Program (Major Technological Innovation Project)[2021CXGC010508] ; Leading Talents in Science and Technology Innovation of Ten Thousand Talents Program in Zhejiang Province[2019R52018] |
| WOS研究方向 | Research & Experimental Medicine ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000838910900006 |
| 出版者 | ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/302341]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Lin, Han-bin; Yang, Ke |
| 作者单位 | 1.Chinese Acad Med Sci, Inst Med Informat, Beijing 100020, Peoples R China 2.China Acad Chinese Med Sci, Natl Resource Ctr Chinese Mat Med, State Key Lab Breeding Base Dao di Herbs, Beijing 100700, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China 4.Chinese Acad Sci, Zhongshan Inst Drug Discovery, SIMM, Zhongshan 528400, Guangdong, Peoples R China 5.China Jiliang Univ, Coll Life Sci, Zhejiang Prov Key Lab Biometrol & Inspection & Qua, Hangzhou 310018, Peoples R China 6.Open Univ China, Coll Agroforestry & Med, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Feng, Li,Wang, Yue,Yang, Jian,et al. Overview of the preparation method, structure and function, and application of natural peptides and polypeptides[J]. BIOMEDICINE & PHARMACOTHERAPY,2022,153:7. |
| APA | Feng, Li.,Wang, Yue.,Yang, Jian.,Sun, Yi-fan.,Li, Yi-wei.,...&Yang, Ke.(2022).Overview of the preparation method, structure and function, and application of natural peptides and polypeptides.BIOMEDICINE & PHARMACOTHERAPY,153,7. |
| MLA | Feng, Li,et al."Overview of the preparation method, structure and function, and application of natural peptides and polypeptides".BIOMEDICINE & PHARMACOTHERAPY 153(2022):7. |
入库方式： OAI收割
来源：上海药物研究所
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