Global spatiotemporal transmission patterns of human enterovirus 71 from 1963 to 2019
文献类型：期刊论文
| 作者 | Xu, Bing1,2,3,4; Wang, Jinfeng1,3; Yan, Bin1,3; Xu, Chengdong3; Yin, Qian3; Yang, Deyan5 |
| 刊名 | VIRUS EVOLUTION
 |
| 出版日期 | 2021-12-01 |
| 卷号 | 7期号:2页码:17 |
| 关键词 | enterovirus 71 hand foot mouth disease phylogeographic analysis spatial transmission |
| DOI | 10.1093/ve/veab071 |
| 通讯作者 | Wang, Jinfeng(wangjf@lreis.ac.cn) |
| 英文摘要 | Enterovirus 71 (EV71) can cause large outbreaks of hand, foot, and mouth disease (HFMD) and severe neurological diseases, which is regarded as a major threat to public health, especially in Asia-Pacific regions. However, the global spatiotemporal spread of this virus has not been identified. In this study, we used large sequence datasets and a Bayesian phylogenetic approach to compare the molecular epidemiology and geographical spread patterns of different EV71 subgroups globally. The study found that subgroups of HFMD presented global spatiotemporal variation, subgroups B0, B1, and B2 have caused early infections in Europe and America, and then subgroups C1, C2, C3, and C4 replaced B0-B2 as the predominant genotypes, especially in Asia-Pacific countries. The dispersal patterns of genotype B and subgroup C4 showed the complicated routes in Asia and the source might in some Asian countries, while subgroups C1 and C2 displayed more strongly supported pathways globally, especially in Europe. This study found the predominant subgroup of EV71 and its global spatiotemporal transmission patterns, which may be beneficial to reveal the long-term global spatiotemporal transmission patterns of human EV71 and carry out the HFMD vaccine development. |
| WOS关键词 | ACUTE FLACCID PARALYSIS ; MOUTH-DISEASE ; MOLECULAR EPIDEMIOLOGY ; GENETIC-ANALYSIS ; PHYLOGENETIC ANALYSIS ; COXSACKIEVIRUS A16 ; 2008 OUTBREAK ; VP1 REGION ; HAND ; FOOT |
| 资助项目 | National Natural Science Foundation of China[41531179] ; Ministry of Science and Technology of China[2016YFC1302504] |
| WOS研究方向 | Virology |
| 语种 | 英语 |
| 出版者 | OXFORD UNIV PRESS |
| WOS记录号 | WOS:000757131800022 |
| 资助机构 | National Natural Science Foundation of China ; Ministry of Science and Technology of China |
| 源URL | [http://ir.igsnrr.ac.cn/handle/311030/171022]  |
| 专题 | 中国科学院地理科学与资源研究所 |
| 通讯作者 | Wang, Jinfeng |
| 作者单位 | 1.Univ Chinese Acad Sci, Sino Danish Coll, 19A Yuquan Rd, Beijing, Peoples R China 2.Xi An Jiao Tong Univ, Affiliated Hosp 1, Dept Infect Dis, 277 Yanta West Rd, Xian 710061, Peoples R China 3.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, State Key Lab Resources & Environm Informat Syst, 11A Datun Rd, Beijing 100101, Peoples R China 4.Key Clin Discipline Natl Hlth Commiss, 277 Yanta West Rd, Xian 710061, Peoples R China 5.China Univ Petr, Coll Oceanog & Space Informat, 66 Changjiangxi Rd, Qingdao 266580, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Bing,Wang, Jinfeng,Yan, Bin,et al. Global spatiotemporal transmission patterns of human enterovirus 71 from 1963 to 2019[J]. VIRUS EVOLUTION,2021,7(2):17. |
| APA | Xu, Bing,Wang, Jinfeng,Yan, Bin,Xu, Chengdong,Yin, Qian,&Yang, Deyan.(2021).Global spatiotemporal transmission patterns of human enterovirus 71 from 1963 to 2019.VIRUS EVOLUTION,7(2),17. |
| MLA | Xu, Bing,et al."Global spatiotemporal transmission patterns of human enterovirus 71 from 1963 to 2019".VIRUS EVOLUTION 7.2(2021):17. |
入库方式： OAI收割
来源：地理科学与资源研究所
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