Effect of dietary supplements on Se bioavailability: A comprehensive in vitro and in vivo study
文献类型：期刊论文
| 作者 | Zhang, Ru2; Yang, Yi1,2; Min, Meng1,2; Li, Yonghua2,3 |
| 刊名 | ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
 |
| 出版日期 | 2022-02-01 |
| 卷号 | 231页码:9 |
| 关键词 | Bioaccessibility Dietary supplements In vitro simulation test Model animal experiment Selenium |
| ISSN号 | 0147-6513 |
| DOI | 10.1016/j.ecoenv.2022.113193 |
| 通讯作者 | Li, Yonghua(yhli@igsnrr.ac.cn) |
| 英文摘要 | Selenium (Se) is an essential micronutrient for animals and humans, and it is present in many different forms with different levels of bioaccessibility in food. Based on the maldistribution of Se and overall low level of Se dietary intake in China, an integrated study was conducted in this thesis to provide references for the regulation of Se nutrition. An in vitro simulation test was used to monitor the concentration effects, the impacts of dietary supplement combinations on the bioaccessibility of Se were examined in rice, and a model animal experiment (in vivo) was used to evaluate the practicability of the Se nutrition regulation scheme. The main results were as follows: the bioaccessibility of Se was effectively increased by 30 mg.d(-1) VE (VE), 300 mg.d(-1) VC + 300 mu g.d(-1) VB9 (VC+VB9) and 30 mg.d(-1) VE + 300 mg.d(-1) VC + 300 mu g.d(-1) VB9 (3IN1) (P < 0.05). The results of the healthy broiler tests showed that the 3 treatments increased the weight and Se content of the broilers, and 3IN1 had the most significant effect (P < 0.05). VC+VB9 was the best at promoting GPx activity, while 3IN1 was the best at promoting SOD activity and the inhibition of MDA content in broilers. The results suggested that VE, VC+VB9 and 3IN1 can benefit the bioavailability of Se and the antioxidant capacity of the body. The results can be used as a scientific reference for Se nutrition regulation. |
| WOS关键词 | HUMAN HEALTH ; VITAMIN-C ; SELENIUM ; SOIL |
| 资助项目 | Second Tibetan Plateau Scientific Expedition and Research Program[2019QZKK0607] ; National Natural Science Foundation of China[42077428] ; National Natural Science Foundation of China[41671499] |
| WOS研究方向 | Environmental Sciences & Ecology ; Toxicology |
| 语种 | 英语 |
| WOS记录号 | WOS:000784301900004 |
| 出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
| 资助机构 | Second Tibetan Plateau Scientific Expedition and Research Program ; National Natural Science Foundation of China |
| 源URL | [http://ir.igsnrr.ac.cn/handle/311030/174313]  |
| 专题 | 中国科学院地理科学与资源研究所 |
| 通讯作者 | Li, Yonghua |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Key Lab Land Surface Pattern & Simulat, Beijing 100101, Peoples R China 3.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, 11A Datun Rd, Beijing 100101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Ru,Yang, Yi,Min, Meng,et al. Effect of dietary supplements on Se bioavailability: A comprehensive in vitro and in vivo study[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2022,231:9. |
| APA | Zhang, Ru,Yang, Yi,Min, Meng,&Li, Yonghua.(2022).Effect of dietary supplements on Se bioavailability: A comprehensive in vitro and in vivo study.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,231,9. |
| MLA | Zhang, Ru,et al."Effect of dietary supplements on Se bioavailability: A comprehensive in vitro and in vivo study".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 231(2022):9. |
入库方式： OAI收割
来源：地理科学与资源研究所
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