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A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility
文献类型：期刊论文
| 作者 | Zhang L; Liu WW ; Yue CG; Zhang TH(张泰华); Li P; Xing ZW; Chen Y
|
| 刊名 | CARBON
 |
| 出版日期 | 2013-09 |
| 卷号 | 61页码:105-115 |
| 通讯作者邮箱 | chenyao@suda.edu.cn |
| 关键词 | HA Coatings Hydroxyapatite Nanocomposites Mineralization Nanoindentation |
| ISSN号 | 0008-6223 |
| 产权排序 | [Zhang, Lv; Liu, Weiwei; Yue, Chunguang; Li, Pei; Xing, Zhanwen; Chen, Yao] Soochow Univ, Sch Mech & Elect Engn, Biomfg Res Ctr, Suzhou 215021, Peoples R China; [Zhang, Taihua] Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100191, Peoples R China |
| 通讯作者 | Chen, Y (reprint author), Soochow Univ, Sch Mech & Elect Engn, Biomfg Res Ctr, 178 East Ganjiang Rd, Suzhou 215021, Peoples R China. |
| 合作状况 | 国内 |
| 中文摘要 | Mechanical properties and in vitro biocompatibility of graphene/hydroxyapatite (HA) composite synthesized using spark plasma sintering (SPS) are reported in this study. Raman spectroscopy corroborated that graphene nanosheets (GNSs) survived the harsh processing conditions of the selected SPS processing parameters. A 1.0 wt.% GNS/HA composite exhibits similar to 80% improvement in fracture toughness as compared to pure HA. GNS pull-out, grain bridging by GNS, crack bridging and crack deflection are the major toughening mechanisms that resist crack propagation. In vitro osteoblast growth tests illustrate that the added GNSs contribute to the improvement of both osteoblast adhesion and apatite mineralization. Therefore, the GNS/HA composite is expected to be a promising material for load-bearing orthopedic implants. (C) 2013 Elsevier Ltd. All rights reserved. |
| 学科主题 | 实验固体力学 |
| 分类号 | 一类 |
| 收录类别 | SCI ; EI |
| 资助信息 | National Natural Science Foundation of China [51275326, 11025212, 11272318]; Natural Science Foundation of Jiangsu Province of China [SBK2010212]; Opening fund of The State Key Laboratory of Nonlinear Mechanics |
| 原文出处 | http://dx.doi.org/10.1016/j.carbon.2013.04.074 |
| 语种 | 英语 |
| WOS记录号 | WOS:000322208700011 |
| 公开日期 | 2013-10-11 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/47477]  |
| 专题 | 力学研究所_非线性力学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhang L,Liu WW,Yue CG,et al. A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility[J]. CARBON,2013,61:105-115. |
| APA | Zhang L.,Liu WW.,Yue CG.,张泰华.,Li P.,...&Chen Y.(2013).A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility.CARBON,61,105-115. |
| MLA | Zhang L,et al."A tough graphene nanosheet/hydroxyapatite composite with improved in vitro biocompatibility".CARBON 61(2013):105-115. |
入库方式： OAI收割
来源：力学研究所
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