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Revisiting the latent structure of negative symptoms in schizophrenia: Evidence from two second-generation clinical assessments br

文献类型：期刊论文

作者Li, Shuai-biao10; Liu, Chao; Zhang, Jian-biao9; Wang, Ling-ling7,8; Hu, Hui-xin7,8; Chu, Min-yi10; Wang, Yi7,8; Lv, Qin-yu6,10; Lui, Simon S. Y.5; Cheung, Eric F. C.4
刊名SCHIZOPHRENIA RESEARCH
出版日期2022-10-01
卷号248页码:131-139
ISSN号0920-9964
关键词Negative symptoms Diminished expression Motivation and pleasure
DOI10.1016/j.schres.2022.08.016
通讯作者Yi, Zheng-hui(yizhenghui1971@163.com) ; Chan, Raymond C. K.(rckchan@psych.ac.cn)
英文摘要Background: Negative symptoms are core symptom of schizophrenia, and many previous research studied the latent structure of negative symptoms based on a single measurement scale. Applying two second-generation negative symptom scales to the same sample can address measurement-invariance of latent structure.Methods: Three-hundred-and-five schizophrenia patients were assessed using the CAINS and the BNSS. Confirmatory Factor Analysis (CFA) tested four competing factor-models: (1) a 1-factor model; (2) a 2-factor model comprising the motivation and pleasure (MAP) domain and the diminished expression (EXP) domain; (3) a 5-factor model comprising anhedonia, avolition, asociality, blunted affect and alogia; (4) a hierarchical model comprising the "first-order" 5-domain factors and the "second-order" MAP & EXP factors.Results: The CFA results for the data of the CAINS showed that the 2-factor model had the best data fit over the other competing models. The CFA using the BNSS data in the same sample also supported the superiority of the 2factor model. Lastly, after combining the items of the BNSS and CAINS together in the same sample for CFA, the 2-factor model prevailed over the other competing models.Conclusions: The 2-factor model appears to be measurement-invariant latent structure of negative symptoms. The novel method of combining the items of the CAINS and BNSS might have circumvented the possible imperfect construct of a single scale. Our findings support the MAP and EXP factors as the latent structure for negative symptoms.
收录类别SCI
WOS关键词ASSESSMENT INTERVIEW ; FACTORIAL STRUCTURE ; FIT INDEXES ; HIGH-RISK ; VALIDATION ; SCALE ; DEFINITION ; EXPERIENCE ; TRIALS
资助项目Jiangsu Provincial Key Research and Development Program[BE2020661] ; Science Foundation of Shanghai Mental Health Centre[SMHCRSD01] ; CAS Key Laboratory of Mental Health, Institute of Psychology ; Philip K. H. Wong Foundation ; Natural Science Foundation of Shanghai science and technology innovation action plan[21ZR1455400] ; Medical Cross Research Fund Project of Star of Jiaotong University of Shanghai Jiaotong University[YG2019QNB07] ; Open Project Program of Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education[2019GDND02]
WOS研究方向Psychiatry
语种英语
出版者ELSEVIER
WOS记录号WOS:000863054000006
资助机构Jiangsu Provincial Key Research and Development Program ; Science Foundation of Shanghai Mental Health Centre ; CAS Key Laboratory of Mental Health, Institute of Psychology ; Philip K. H. Wong Foundation ; Natural Science Foundation of Shanghai science and technology innovation action plan ; Medical Cross Research Fund Project of Star of Jiaotong University of Shanghai Jiaotong University ; Open Project Program of Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education
源URL[http://ir.psych.ac.cn/handle/311026/43631]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Yi, Zheng-hui; Chan, Raymond C. K.
作者单位1.Chinese Acad Sci, Inst Psychol, 16 Lincui Rd, Beijing 100101, Peoples R China
2.Shanghai Mental Hlth Ctr, 600 South Wanping Rd, Shanghai, Peoples R China
3.Fudan Univ, Inst Mental Hlth, Shanghai, Peoples R China
4.Castle Peak Hosp, Hong Kong, Peoples R China
5.Univ Hong Kong, Sch Clin Med, Dept Psychiat, Hong Kong, Peoples R China
6.Fudan Univ, Huashan Hosp, Sch Med, Dept Psychiat, Shanghai, Peoples R China
7.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
8.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Beijing, Peoples R China
9.Nantong Fourth Peoples Hosp, Jiangsu, Peoples R China
10.Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Sch Med, Shanghai, Peoples R China
推荐引用方式
GB/T 7714		 Li, Shuai-biao,Liu, Chao,Zhang, Jian-biao,et al. Revisiting the latent structure of negative symptoms in schizophrenia: Evidence from two second-generation clinical assessments br[J]. SCHIZOPHRENIA RESEARCH,2022,248:131-139.
APA Li, Shuai-biao.,Liu, Chao.,Zhang, Jian-biao.,Wang, Ling-ling.,Hu, Hui-xin.,...&Chan, Raymond C. K..(2022).Revisiting the latent structure of negative symptoms in schizophrenia: Evidence from two second-generation clinical assessments br.SCHIZOPHRENIA RESEARCH,248,131-139.
MLA Li, Shuai-biao,et al."Revisiting the latent structure of negative symptoms in schizophrenia: Evidence from two second-generation clinical assessments br".SCHIZOPHRENIA RESEARCH 248(2022):131-139.

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来源：心理研究所

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