Disruption of dynamic functional connectivity in children with developmental dyslexia
文献类型：期刊论文
| 作者 | Li, Yizhen1,2; Li, Junjun1,2 ; Yang, Yang1,2; Bi, Hong-Yan1,2
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| 刊名 | LANGUAGE COGNITION AND NEUROSCIENCE
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| 出版日期 | 2022-10-01 |
| 页码 | 15 |
| ISSN号 | 2327-3798 |
| 关键词 | Developmental dyslexia resting-state fMRI dynamic functional connectivity temporal variability |
| DOI | 10.1080/23273798.2022.2129084 |
| 通讯作者 | Yang, Yang(yangyang@psych.ac.cn) ; Bi, Hong-Yan(bihy@psych.ac.cn) |
| 英文摘要 | Developmental dyslexia (DD) is the most common learning disorder. The alternations of intrinsic functional connectivity (FC) have been frequently reported to be associated with DD. However, previous research has predominately focused on static FC features. Using functional magnetic resonance imaging and a sliding time window approach, this study examined dynamic FC during rest in 22 children with DD and 38 age-matched controls. Results showed that compared to controls, dyslexic children exhibited increased temporal variability of FC in the left inferior frontal gyrus (IFG). Moreover, the higher dynamics of FC was correlated with poorer reading performance, confirming the role of atypical dynamic FC in DD. We found that the altered dynamic FC in dyslexics was associated with problematic regional activity and functional-structural coupling. This study for the first time reveals the aberrant dynamic FC in a pivotal language region, providing novel insights into the neural signature of DD. |
| 收录类别 | SCI |
| WOS关键词 | ATTENTION-DEFICIT/HYPERACTIVITY DISORDER ; HUMAN BRAIN NETWORKS ; RESTING-STATE ; CHINESE CHARACTERS ; VARIABILITY ; METAANALYSIS ; FMRI ; ABNORMALITIES ; ORGANIZATION ; DEFICITS |
| 资助项目 | National Natural Science Foundation of China[31671155] ; National Natural Science Foundation of China[31800954] |
| WOS研究方向 | Audiology & Speech-Language Pathology ; Behavioral Sciences ; Linguistics ; Psychology |
| 语种 | 英语 |
| 出版者 | ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD |
| WOS记录号 | WOS:000864811200001 |
| 资助机构 | National Natural Science Foundation of China |
| 源URL | [http://ir.psych.ac.cn/handle/311026/43525]  |
| 专题 | 心理研究所_中国科学院行为科学重点实验室 |
| 通讯作者 | Yang, Yang; Bi, Hong-Yan |
| 作者单位 | 1.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Ctr Brain Sci & Learning Difficulties, CAS Key Lab Behav Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Yizhen,Li, Junjun,Yang, Yang,et al. Disruption of dynamic functional connectivity in children with developmental dyslexia[J]. LANGUAGE COGNITION AND NEUROSCIENCE,2022:15. |
| APA | Li, Yizhen,Li, Junjun,Yang, Yang,&Bi, Hong-Yan.(2022).Disruption of dynamic functional connectivity in children with developmental dyslexia.LANGUAGE COGNITION AND NEUROSCIENCE,15. |
| MLA | Li, Yizhen,et al."Disruption of dynamic functional connectivity in children with developmental dyslexia".LANGUAGE COGNITION AND NEUROSCIENCE (2022):15. |
入库方式： OAI收割
来源：心理研究所
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