Investigation of peptoid chiral stationary phases varied in absolute configuration
文献类型：期刊论文
| 作者 | Wu, Haibo1; Li, Kuiyong1; Yu, Hui1; Ke, Yanxiong1; Liang, Xinmiao1,2 |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2013-03-15 |
| 卷号 | 1281页码:155-159 |
| 关键词 | Peptoid Oligopeptoid Diastereoisomeric selectors Chiral stationary phase |
| 产权排序 | 2,5 |
| 通讯作者 | 柯燕雄 ; 梁鑫淼 |
| 英文摘要 | based on chiral n-(1-phenylethyl) glycines, a series of peptoid chiral stationary phases (csps) terminated with achiral alkyl group (diisopropyl, t-butyl or n-butyl) and varied in absolute configuration of selector were investigated with nine axially chiral analytes. it is very interesting to observe that selectors with heterogeneous configuration form, such as s-r-r, s-r-s, s-s-r, generally performed better than s-s-s selectors. moreover, longer s-r-s-r-s selector did not outperform the s-r-s one obviously, with several separations declined. in addition to the result that the elution order of most enantiomers depends on the asymmetric center adjacent to the terminus of selector, we presume that the moieties around this chiral center are the most important absorbing sites for chiral discrimination; the terminal group and other chiral blocks in selector may assist enantiorecognition by constructing appropriate conformation. various terminal alkyl groups also resulted in a few differences in enantioselectivity. (c) 2013 published by elsevier b.v. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 学科主题 | 物理化学 |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | performance liquid-chromatography ; varying peptide length ; capillary-electrophoresis ; side-chains ; recognition ; selectors ; enantiomers ; separation ; hplc ; enantioseparations |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000315552700021 |
| 公开日期 | 2013-10-11 |
| 源URL | [http://159.226.238.44/handle/321008/117620]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.E China Univ Sci & Technol, Sch Pharm, Minist Educ, Engn Res Ctr Pharmaceut Proc Chem, Shanghai 200237, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Haibo,Li, Kuiyong,Yu, Hui,et al. Investigation of peptoid chiral stationary phases varied in absolute configuration[J]. journal of chromatography a,2013,1281:155-159. |
| APA | Wu, Haibo,Li, Kuiyong,Yu, Hui,Ke, Yanxiong,&Liang, Xinmiao.(2013).Investigation of peptoid chiral stationary phases varied in absolute configuration.journal of chromatography a,1281,155-159. |
| MLA | Wu, Haibo,et al."Investigation of peptoid chiral stationary phases varied in absolute configuration".journal of chromatography a 1281(2013):155-159. |
入库方式： OAI收割
来源：大连化学物理研究所
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