Study of stereomeric peptoid chiral stationary phases containing different chiral side chains
文献类型：期刊论文
| 作者 | Wu, Haibo1; Song, Guangjun1; Wang, Dongqiang1; Yu, Hui1; Ke, Yanxiong1; Liang, Xinmiao1,2 |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2013-07-12 |
| 卷号 | 1298页码:152-156 |
| 关键词 | Peptoid Enantiomeric separation Stereomeric selectors Chiral stationary phase |
| 产权排序 | 2,6 |
| 通讯作者 | 柯燕雄 ; 梁鑫淼 |
| 英文摘要 | in this study, we investigated six stereomeric peptoid chiral stationary phases (csps) successively combining n'-phenyl-proline amide, alpha-phenylethyl amine, 2-amino cyclohexyl phenylcarbamate and another a-phenylethyl amine under normal phase mode. csps 1-4 with r-s-(r,r)-s, r-s-(s,s)-s, r-r-(r,r)-r and r-r-(s,s)-r configuration exhibited much different enantiorecognition abilities. overall, csps 1 and 2 performed better for the 55 analytes tested. csp 5 with mixed selectors combined partial selectivities of csps 1 and 2. csp 6 as enantiomeric counterpart of csp 2 exhibited similar enantioseparation ability and reversal elution orders for analytes resolved. for several biaryl type analytes, csp 6 even outperformed commercial chiralpak ad-h and chiralcel od-h. excellent resolution of 3,3'-diphenyl-2,2'-bi-1-naphthalol (vanol) on csp 6 illustrated its potential application in preparative enantioseparation. eluting orders of enantiomers on stereomeric csps also provided us further insight into enantiorecognition of some analytes. (c) 2013 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 学科主题 | 物理化学 |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | enantiomeric separations ; absolute-configuration ; improvement ; resolution ; selector ; acids ; hplc |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000321174700019 |
| 公开日期 | 2013-10-11 |
| 源URL | [http://159.226.238.44/handle/321008/117661]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.E China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Minist Educ, Sch Pharm, Shanghai 200237, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Haibo,Song, Guangjun,Wang, Dongqiang,et al. Study of stereomeric peptoid chiral stationary phases containing different chiral side chains[J]. journal of chromatography a,2013,1298:152-156. |
| APA | Wu, Haibo,Song, Guangjun,Wang, Dongqiang,Yu, Hui,Ke, Yanxiong,&Liang, Xinmiao.(2013).Study of stereomeric peptoid chiral stationary phases containing different chiral side chains.journal of chromatography a,1298,152-156. |
| MLA | Wu, Haibo,et al."Study of stereomeric peptoid chiral stationary phases containing different chiral side chains".journal of chromatography a 1298(2013):152-156. |
入库方式： OAI收割
来源：大连化学物理研究所
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