Rearranged Dichapetalin-Type Triterpenoids with Cytotoxic Activity from Dichapetalum gelonioides
文献类型：期刊论文
| 作者 | Gao, Xin-Hua3; Wang, Xi-Yuan3; Zhou, Jun-Su3; Zhang, Yan3; Liu, Hong-Chun3 ; Zhou, Bin1,3; Yue, Jian-Min1,2,3
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| 刊名 | CHINESE JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2022-08-16 |
| 页码 | 8 |
| 关键词 | Dichapetalum gelonioides Natural products Dichapetalin-type triterpenoids Structural elucidation Cytotoxic activity |
| ISSN号 | 1001-604X |
| DOI | 10.1002/cjoc.202200383 |
| 通讯作者 | Zhou, Bin(zbbrush@simm.ac.cn) ; Yue, Jian-Min(jmyue@simm.ac.cn) |
| 英文摘要 | Comprehensive Summary Dichagelinoids A-C (1-3), three unusual dichapetalin-type triterpenoids, together with two biogenetically related derivatives dichagelinoids D and E (4 and 5) were isolated and characterized by solid data from Dichapetalum gelonioides. Compounds 1-3 possess a common rearranged C ring and different C6-C2 modified motifs at the A rings. Biological evaluation revealed that compounds 1-3 showed distinct cytotoxic activity against the tested human cancer cell lines. |
| 资助项目 | National Natural Science Foundation of China[22007095] ; CAMS Innovation Fund for Medical Sciences[2019-I2M-5-080] ; Biological Resources Program, CAS of People's Republic of China[KFJ-BRP-008-001] ; Youth Innovation Promotion Association of CAS[2022283] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000851534400001 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/302407]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Zhou, Bin; Yue, Jian-Min |
| 作者单位 | 1.Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai 264117, Shandong, Peoples R China 2.Chinese Acad Med Sci, Res Units Discovery New Drug Lead Mol, Beijing, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, Xin-Hua,Wang, Xi-Yuan,Zhou, Jun-Su,et al. Rearranged Dichapetalin-Type Triterpenoids with Cytotoxic Activity from Dichapetalum gelonioides[J]. CHINESE JOURNAL OF CHEMISTRY,2022:8. |
| APA | Gao, Xin-Hua.,Wang, Xi-Yuan.,Zhou, Jun-Su.,Zhang, Yan.,Liu, Hong-Chun.,...&Yue, Jian-Min.(2022).Rearranged Dichapetalin-Type Triterpenoids with Cytotoxic Activity from Dichapetalum gelonioides.CHINESE JOURNAL OF CHEMISTRY,8. |
| MLA | Gao, Xin-Hua,et al."Rearranged Dichapetalin-Type Triterpenoids with Cytotoxic Activity from Dichapetalum gelonioides".CHINESE JOURNAL OF CHEMISTRY (2022):8. |
入库方式： OAI收割
来源：上海药物研究所
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