Frequency Distribution of the Amide-I Vibration Sorted by Residues in Amyloid Fibrils Revealed by 2D-IR Measurements and Simulations
文献类型：期刊论文
| 作者 | Falvo, Cyril1; Zhuang, Wei2; Kim, Yung Sam3,4; Axelsen, Paul H.5; Hochstrasser, Robin M.3; Mukamel, Shaul6 |
| 刊名 | journal of physical chemistry b
 |
| 出版日期 | 2012-03-15 |
| 卷号 | 116期号:10页码:3322-3330 |
| 产权排序 | 2,2 |
| 通讯作者 | cyrilfalvo |
| 英文摘要 | the infrared optical response of amyloid fibrils a beta(1-40) is investigated. simulations of two models corresponding to different protonation states are compared with experiment. the simulations reveal that vibrational frequency distributions inside the fibrils are dominated by side chain fluctuations. we further confirm earlier suggestions based on 2d-ir measurements that water molecules can be trapped inside the fibrils. |
| WOS标题词 | science & technology ; physical sciences |
| 学科主题 | 物理化学 |
| 类目[WOS] | chemistry, physical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | 2-dimensional infrared-spectroscopy ; hydrogen-bond dynamics ; particle mesh ewald ; 2d ir ; molecular-dynamics ; experimental constraints ; alzheimers-disease ; provides evidence ; line-shapes ; peptide |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000301509500029 |
| 公开日期 | 2013-10-11 |
| 源URL | [http://159.226.238.44/handle/321008/117736]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Univ Paris 11, Inst Sci Mol Orsay, CNRS, UMR 8214, F-91405 Orsay, France 2.Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, LiaoNing, Peoples R China 3.Univ Penn, Dept Chem, Philadelphia, PA 19104 USA 4.Ulsan Natl Inst Sci & Technol, Sch Nanobiosci & Chem Engn, Seoul, South Korea 5.Univ Penn, Sch Med, Dept Pharmacol Biochem & Biophys, Philadelphia, PA 19104 USA 6.Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA |
| 推荐引用方式 GB/T 7714 | Falvo, Cyril,Zhuang, Wei,Kim, Yung Sam,et al. Frequency Distribution of the Amide-I Vibration Sorted by Residues in Amyloid Fibrils Revealed by 2D-IR Measurements and Simulations[J]. journal of physical chemistry b,2012,116(10):3322-3330. |
| APA | Falvo, Cyril,Zhuang, Wei,Kim, Yung Sam,Axelsen, Paul H.,Hochstrasser, Robin M.,&Mukamel, Shaul.(2012).Frequency Distribution of the Amide-I Vibration Sorted by Residues in Amyloid Fibrils Revealed by 2D-IR Measurements and Simulations.journal of physical chemistry b,116(10),3322-3330. |
| MLA | Falvo, Cyril,et al."Frequency Distribution of the Amide-I Vibration Sorted by Residues in Amyloid Fibrils Revealed by 2D-IR Measurements and Simulations".journal of physical chemistry b 116.10(2012):3322-3330. |
入库方式： OAI收割
来源：大连化学物理研究所
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