Integrated application of transcriptomics and metabolomics provides insights into condition index difference mechanisms in the Pacific oyster (Crassostrea gigas)
文献类型：期刊论文
| 作者 | He, Xin1,4,5,6; Wu, Fucun1,2,5,6; Wang, Luping6; Li, Li2,3,6; Zhang, Guofan2,5,6 |
| 刊名 | GENOMICS
 |
| 出版日期 | 2022-07-01 |
| 卷号 | 114期号:4页码:13 |
| 关键词 | Crassostrea gigas Condition index Transcriptomics Metabolomics Seafood |
| ISSN号 | 0888-7543 |
| DOI | 10.1016/j.ygeno.2022.110413 |
| 通讯作者 | Wu, Fucun(wufucun@qdio.ac.cn) |
| 英文摘要 | The condition index (CI) is an economically important tool for assessing the quality of oysters, such as the Pacific oyster Crassostrea gigas. However, little is known about the mechanisms that underlie differences in CI between different C. gigas populations. In this study, we integrated transcriptomic and metabolomic profiling to investigate the mechanisms that underlie the differences between high- and low-CI groups in one- and two-year-old populations of C. gigas. The results indicate that differences in CI were associated with the regulation of growth-related genes, the FoxO signaling pathway, and the complex regulation of carbohydrate, lipid, amino acid, and energy metabolism. Moreover, the mechanisms underlying these differences differed between the populations. This study is the first to elucidate the molecular and chemical mechanisms associated with CI, and the results will be helpful for breeding higher quality oysters. |
| 资助项目 | Strategic Priority Research Program of the Chinese Academy of Sciences[XDA24030105] ; Major Scientific and Technological Innovation Project of Shandong Province[2021LZGC029] ; Major Scientific and Technological Innovation Project of Shandong Province[2019JZZY010813] ; National Key R&D Program of China[2019YFD0900800] ; China Agriculture Research System of MOF and MARA[CARS-49] |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Genetics & Heredity |
| 语种 | 英语 |
| WOS记录号 | WOS:000833424100006 |
| 出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/179857]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Wu, Fucun |
| 作者单位 | 1.Chinese Acad Sci, Innovat Seed Design, Wuhan 430072, Peoples R China 2.Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 5.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China 6.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Xin,Wu, Fucun,Wang, Luping,et al. Integrated application of transcriptomics and metabolomics provides insights into condition index difference mechanisms in the Pacific oyster (Crassostrea gigas)[J]. GENOMICS,2022,114(4):13. |
| APA | He, Xin,Wu, Fucun,Wang, Luping,Li, Li,&Zhang, Guofan.(2022).Integrated application of transcriptomics and metabolomics provides insights into condition index difference mechanisms in the Pacific oyster (Crassostrea gigas).GENOMICS,114(4),13. |
| MLA | He, Xin,et al."Integrated application of transcriptomics and metabolomics provides insights into condition index difference mechanisms in the Pacific oyster (Crassostrea gigas)".GENOMICS 114.4(2022):13. |
入库方式： OAI收割
来源：海洋研究所
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