NIR-II nano fluorescence image guided hepatic carcinoma resection on cirrhotic patient
文献类型:期刊论文
作者 | Zhang, Zeyu2,3; Fang, Cheng4; Zhang, Yang5; Su, Song4; Li, Bo4; Liu, Gang5; Hu, Zhenhua1,3; Tian, Jie2,3 |
刊名 | PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY |
出版日期 | 2022-12-01 |
卷号 | 40页码:3 |
ISSN号 | 1572-1000 |
关键词 | NIR-II fluorescence imaging Hepatic carcinoma (HCC) Cirrhosis Image-guided surgery Nano probe |
DOI | 10.1016/j.pdpdt.2022.103098 |
通讯作者 | Liu, Gang(gangliu.cmitm@xmu.edu) ; Hu, Zhenhua(zhenhua.hu@ia.ac) ; Tian, Jie(tian@ieee.org) |
英文摘要 | Precise resection of hepatic carcinoma (HCC) remains challenging for cirrhotic patients. Cirrhosis not only effects intraoperative palpation, but can also cause severe false-positive problems to indocyanine green (ICG) fluores-cence imaging. Herein, we report the application of a nano-scale probe IgG-IRDye800CW to achieve precise HCC resection from cirrhotic liver. A 66-year-old male patient with liver cancer received intravenous injection of IgG-IRDye800CW (10 mg) 6 days prior to surgery, and none adverse effects were observed. During the operation, the HCC lesion in the right liver lobe was specifically detected on the near-infrared window II (NIR-II) fluorescence images. The high-contrast NIR-II fluorescence delineated a clear margin to improve surgical precision. These clinical observations showed high safety and feasibility of applying IgG-IRDye800CW NIR-II fluorescence im-aging to guide hepatic surgery and minimize hepatic function damage. |
资助项目 | National Key Research and Development Program of China[2017YFA0205200] ; National Natural Science Foundation of China (NSFC)[62027901] ; National Natural Science Foundation of China (NSFC)[92059207] ; National Natural Science Foundation of China (NSFC)[81930048] ; National Natural Science Foundation of China (NSFC)[81930053] ; National Natural Science Foundation of China (NSFC)[81227901] ; National Natural Science Foundation of China (NSFC)[81801864] ; National Natural Science Foundation of China (NSFC)[82102236] ; Chinese Academy of Sciences[QYZDJ-SSW-JSC005] ; CAS Youth Interdisciplinary Team[JCTD-2021-08] ; Beijing Natural Science Foundation[JQ19027] ; China Postdoctoral Science Foundation[2022T150037] ; China Postdoctoral Science Foundation[2021M690007] ; Zhuhai High-level Health Personnel Team Project (Zhuhai)[HLHPTP201703] ; innovative research team of high-level local universities in Shanghai |
WOS研究方向 | Oncology |
语种 | 英语 |
出版者 | ELSEVIER |
WOS记录号 | WOS:000860474600007 |
资助机构 | National Key Research and Development Program of China ; National Natural Science Foundation of China (NSFC) ; Chinese Academy of Sciences ; CAS Youth Interdisciplinary Team ; Beijing Natural Science Foundation ; China Postdoctoral Science Foundation ; Zhuhai High-level Health Personnel Team Project (Zhuhai) ; innovative research team of high-level local universities in Shanghai |
源URL | [http://ir.ia.ac.cn/handle/173211/50409] |
专题 | 自动化研究所_中国科学院分子影像重点实验室 |
通讯作者 | Liu, Gang; Hu, Zhenhua; Tian, Jie |
作者单位 | 1.Univ Chinese Acad Sci, Sch Artificial Intelligence, Beijing, Peoples R China 2.Beihang Univ, Beijing Adv Innovat Ctr Big Data Based Precis Med, Sch Engn Med, Beijing, Peoples R China 3.Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing Key Lab Mol Imaging, Beijing, Peoples R China 4.Southwest Med Univ, Dept Gen Surg Hepatobiliary Surg, Affiliated Hosp, Luzhou, Peoples R China 5.Xiamen Univ, Ctr Mol Imaging & Translat Med, Sch Publ Hlth, State Key Lab Mol Vaccinol & Mol Diag, Xiamen, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Zeyu,Fang, Cheng,Zhang, Yang,et al. NIR-II nano fluorescence image guided hepatic carcinoma resection on cirrhotic patient[J]. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY,2022,40:3. |
APA | Zhang, Zeyu.,Fang, Cheng.,Zhang, Yang.,Su, Song.,Li, Bo.,...&Tian, Jie.(2022).NIR-II nano fluorescence image guided hepatic carcinoma resection on cirrhotic patient.PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY,40,3. |
MLA | Zhang, Zeyu,et al."NIR-II nano fluorescence image guided hepatic carcinoma resection on cirrhotic patient".PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY 40(2022):3. |
入库方式: OAI收割
来源:自动化研究所
浏览0
下载0
收藏0
其他版本
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。