Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation
文献类型:期刊论文
作者 | Qin, Hongqiang; Wang, Fangjun; Zhang, Yi; Hu, Zhengyan; Song, Chunxia; Wu, Ren'an; Ye, Mingliang; Zou, Hanfa |
刊名 | chemical communications
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出版日期 | 2012 |
卷号 | 48期号:50页码:6265-6267 |
ISSN号 | 1359-7345 |
产权排序 | 1,1 |
通讯作者 | 邹汉法 |
英文摘要 | highly site-selective dimethyl labeling of n-terminus of peptides has been obtained by adjusting the acidic strength of the reaction solution. and this selective labeling strategy combined with the use of different isotope formaldehyde reagents has been successfully used in the proteome quantification by using the isobaric peptide cross-sequence labeling method, which would play increasingly important roles in the clinical diagnosis, especially in the discovery of biomarkers for diseases. |
WOS标题词 | science & technology ; physical sciences |
学科主题 | 物理化学 |
类目[WOS] | chemistry, multidisciplinary |
研究领域[WOS] | chemistry |
关键词[WOS] | organocatalytic reductive amination ; quantitative proteomics ; cleavage sites ; living cells ; protein |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000304486800018 |
公开日期 | 2013-10-11 |
源URL | [http://159.226.238.44/handle/321008/117941] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | Chinese Acad Sci, CAS Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
推荐引用方式 GB/T 7714 | Qin, Hongqiang,Wang, Fangjun,Zhang, Yi,et al. Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation[J]. chemical communications,2012,48(50):6265-6267. |
APA | Qin, Hongqiang.,Wang, Fangjun.,Zhang, Yi.,Hu, Zhengyan.,Song, Chunxia.,...&Zou, Hanfa.(2012).Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation.chemical communications,48(50),6265-6267. |
MLA | Qin, Hongqiang,et al."Isobaric cross-sequence labeling of peptides by using site-selective N-terminus dimethylation".chemical communications 48.50(2012):6265-6267. |
入库方式: OAI收割
来源:大连化学物理研究所
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