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Green synthesis of ultrasmall selenium nanoparticles (SeNPs) using Hericium erinaceus polysaccharide (HEP) as nanozymes for efficient intracellular antioxidation

文献类型：期刊论文

作者He, Huaqi1,2; Liu, Chao2,3; Shao, Changsheng2,3; Wu, Yahui2,3; Huang, Qing1,2,3
刊名MATERIALS LETTERS
出版日期2022-06-15
卷号317
关键词Selenium Nanoparticles (NPs) Nanozymes Hericium erinaceus polysaccharide (HEP) Biomaterials Antioxidant
ISSN号0167-577X
DOI10.1016/j.matlet.2022.132079
通讯作者Huang, Qing(huangq@ipp.ac.cn)
英文摘要As one of essential trace elements for the human body, selenium plays an important role in antioxidation by scavenging free radicals. Especially, selenium nanoparticles (SeNPs) nowadays attract increasing attention due to their low toxicity and high biocompatibility. In this work, we introduced a facile method of green synthesis of ultra-small monodisperse SeNPs using Hericium erinaceus polysaccharides (HEP), and investigated the antioxidant property and biocompatibility of the as-prepared SeNPs. Our results showed that the HEP-SeNPs had the excellent antioxidant ability to eliminate reactive oxygen species (ROS) efficiently, and it could act as mimic enzymes or nanozymes such as catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx). The cell experiment confirmed the outstanding cell protection ability against external oxidative stress. Therefore, this work has not only put forward a facile and efficient method of green synthesis of ultra-small selenium nanoparticles with excellent antioxidant capacity and biocompatibility, but also demonstrated the potential application of the HEP-SeNPs as the nanozymes in biological applications such as strong antioxidants.
WOS关键词SE
资助项目Anhui Provincial Key Research and Development Plan[202004i07020014] ; Research Integration Program of Hefei Institutes of Physical Science, Chinese Academy of Sciences
WOS研究方向Materials Science ; Physics
语种英语
WOS记录号WOS:000810791800003
出版者ELSEVIER
资助机构Anhui Provincial Key Research and Development Plan ; Research Integration Program of Hefei Institutes of Physical Science, Chinese Academy of Sciences
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/129582]  
专题中国科学院合肥物质科学研究院
通讯作者Huang, Qing
作者单位1.Anhui Sci & Technol Univ, Coll Agr, Fengyang 233100, Peoples R China
2.Chinese Acad Sci, Inst Intelligent Machines, Inst Intelligent Agr, Hefei Inst Phys Sci, Hefei 230031, Peoples R China
3.Univ Sci & Technol China, Grad Sch, Sci Isl Branch, Hefei 230026, Peoples R China
推荐引用方式
GB/T 7714		 He, Huaqi,Liu, Chao,Shao, Changsheng,et al. Green synthesis of ultrasmall selenium nanoparticles (SeNPs) using Hericium erinaceus polysaccharide (HEP) as nanozymes for efficient intracellular antioxidation[J]. MATERIALS LETTERS,2022,317.
APA He, Huaqi,Liu, Chao,Shao, Changsheng,Wu, Yahui,&Huang, Qing.(2022).Green synthesis of ultrasmall selenium nanoparticles (SeNPs) using Hericium erinaceus polysaccharide (HEP) as nanozymes for efficient intracellular antioxidation.MATERIALS LETTERS,317.
MLA He, Huaqi,et al."Green synthesis of ultrasmall selenium nanoparticles (SeNPs) using Hericium erinaceus polysaccharide (HEP) as nanozymes for efficient intracellular antioxidation".MATERIALS LETTERS 317(2022).

入库方式： OAI收割

来源：合肥物质科学研究院

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