中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Bibliometric and visual analysis in the field of ketogenic diet on cancer from 2012 to 2021

文献类型:期刊论文

作者Li, Rongrong4; Huang, Qingcheng5; Ye, Chenxiao5; Wu, Changhong6; Luo, Ning3; Lu, Yi1; Fang, Jianqiao4; Wang, Yun2
刊名FRONTIERS IN NUTRITION
出版日期2022-11-10
卷号9
ISSN号2296-861X
关键词bibliometric analysis ketogenic diet cancer mechanism immunotherapy clinical trials
DOI10.3389/fnut.2022.1060436
通讯作者Lu, Yi(luyi@zjcc.org.cn) ; Fang, Jianqiao(fangjianqiao7532@163.com) ; Wang, Yun(wangyun61689756@163.com)
英文摘要Increasing evidence demonstrated that the ketogenic diet (KD) played a positive effect on cancer treatment. However, no systematic review and bibliometric analysis were conducted in this field. This study aimed to explore the current status, and reveal the potential trends and hotspots to provide a reference for future research. Publications were extracted from the Web of Science Core Collection. CiteSpace (5.6.R3) software and the website of bibliometrics were used for visual analysis. A total of 500 publications with 334 articles and 166 reviews were included, with the timespan of 2012 to 2021. The United States was the most productive country. Majority of the top 10 institutions were from the United States, and Harvard University was the top-contributing institution. The most prolific author and the co-cited author was Thomas N Seyfried from Boston College. The highest cited reference was published in PLoS ONE, authored by Abdelwahab Mohammed G, with 161 citations. Glioma and breast cancer were the most common types of cancer in this field, while hepatocellular carcinoma and pancreatic cancer were the new hotspots. The anti-tumor mechanism of KD mainly focused on regulating metabolism, decanoic acid, oxidative stress, fatty acid oxidation, and cell apoptosis. Additionally, the presence of "chemotherapy" and "radiotherapy" in the keywords indicated that KD combined with anti-tumor research was a topic, while "immunotherapy" has became a recent frontiers. Notably, as a metabolic therapy, KD was deserved more attention in the treatment of hepatocellular carcinoma and pancreatic cancer, and KD combined with immunotherapy was the new hotspot and frontier. Additionally, more molecular studies and high-quality uniformly, randomized, controlled clinical trials are urgently warranted to evaluate the effect of KD in multiple cancers.
WOS关键词METABOLICALLY SUPPORTED CHEMOTHERAPY ; HYPERBARIC-OXYGEN THERAPY ; LUNG-CANCER ; HYPERTHERMIA
资助项目Traditional Chinese Medicine Research Program of Zhejiang Province ; Medical and Health Platform Program of Zhejiang Province ; [2018ZQ020] ; [2021KY556]
WOS研究方向Nutrition & Dietetics
语种英语
出版者FRONTIERS MEDIA SA
WOS记录号WOS:000889355200001
资助机构Traditional Chinese Medicine Research Program of Zhejiang Province ; Medical and Health Platform Program of Zhejiang Province
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/131624]  
专题中国科学院合肥物质科学研究院
通讯作者Lu, Yi; Fang, Jianqiao; Wang, Yun
作者单位1.Univ Chinese Acad Sci, Canc Hosp, Zhejiang Canc Hosp, Inst Basic Med & Canc,Dept Clin Nutr, Hangzhou, Peoples R China
2.Zhejiang Chinese Med Univ, Affiliated Hosp 1, Dept Oncol, Hangzhou, Peoples R China
3.Zhejiang Chinese Med Univ, Clin Coll 3, Hangzhou, Peoples R China
4.Zhejiang Chinese Med Univ, Affiliated Hosp 3, Hangzhou, Peoples R China
5.Zhejiang Chinese Med Univ, Clin Coll 1, Hangzhou, Peoples R China
6.Zhejiang Chinese Med Univ, Clin Coll 2, Hangzhou, Peoples R China
推荐引用方式
GB/T 7714
Li, Rongrong,Huang, Qingcheng,Ye, Chenxiao,et al. Bibliometric and visual analysis in the field of ketogenic diet on cancer from 2012 to 2021[J]. FRONTIERS IN NUTRITION,2022,9.
APA Li, Rongrong.,Huang, Qingcheng.,Ye, Chenxiao.,Wu, Changhong.,Luo, Ning.,...&Wang, Yun.(2022).Bibliometric and visual analysis in the field of ketogenic diet on cancer from 2012 to 2021.FRONTIERS IN NUTRITION,9.
MLA Li, Rongrong,et al."Bibliometric and visual analysis in the field of ketogenic diet on cancer from 2012 to 2021".FRONTIERS IN NUTRITION 9(2022).

入库方式: OAI收割

来源:合肥物质科学研究院

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