Long-term anxiety and depression signatures of participants that received esophageal cancer screening: A multicenter population-based cohort study
文献类型：期刊论文
| 作者 | Zhu, Juan3,4; Ma, Shanrui4; Chen, Ru4; Xie, Shuanghua4; Liu, Zhaorui2; Liu, Zhengkui1 ; Wei, Wenqiang4
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| 刊名 | CANCER MEDICINE
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| 出版日期 | 2022-11-24 |
| 页码 | 13 |
| ISSN号 | 2045-7634 |
| 关键词 | anxiety cohort depression endoscopic screening esophageal cancer high-grade intraepithelial neoplasia high-incidence areas long-term psychological distress |
| DOI | 10.1002/cam4.5404 |
| 通讯作者 | Wei, Wenqiang(weiwq@cicams.ac.cn) |
| 英文摘要 | BackgroundCurrent evidence on the psychological impact of screening and diagnosis of esophageal cancer (EC) is limited and unclear. MethodsThis multicenter, population-based, prospective study was conducted in five high-incidence regions in China from 2017 to 2020. The screened participants were diagnosed as healthy, esophagitis, low-grade intraepithelial neoplasia (LGIN), high-grade intraepithelial neoplasia (HGIN), or EC based on pathological biopsy. The psychological impact of the screening was assessed by comparing anxiety and depression symptoms at baseline and follow-up. ResultsA total of 1973 individuals were ultimately included, with an average follow-up of 22.2 months. The prevalence of anxiety and depression symptoms in screened population at baseline was 14.3% and 18.4%. The prevalence of anxiety and depression symptoms of screeners at follow-up declined (all p < 0.001). The anxiety (RR [95% CI]: 0.37 [0.30-0.46]) and depression (0.29 [0.24-0.36]) of screeners weakened over time, but the anxiety and depression symptoms was continuous for patients with HGIN and patients with EC. Compared with the participants classified as normal, the RRs(95% CI) of anxiety and depression symptoms were 2.20 (1.10-4.30) and 2.03 (1.07-3.86) for the patients with HGIN and 2.30 (0.82-6.20) and 3.79 (01.71-8.43) for the patients with EC. ConclusionThe anxiety and depression symptoms of screeners weakened over time, except in patients with HGIN and EC, for whom it remained lasting and high. Psychological assistance and interventions are urgently needed for individuals who are ready for screening and for those diagnosed as having HGIN or EC. |
| 收录类别 | SCI |
| WOS关键词 | PATIENT ANXIETY ; GASTRIC-CANCER ; MORTALITY ; PROGRAM ; STRESS ; CHINA |
| WOS研究方向 | Oncology |
| 语种 | 英语 |
| 出版者 | WILEY |
| WOS记录号 | WOS:000889220300001 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/44028]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 通讯作者 | Wei, Wenqiang |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing, Peoples R China 2.Peking Univ, Minist Hlth, Inst Mental Hlth, Key Lab Mental Hlth, Beijing, Peoples R China 3.Chinese Acad Sci, Canc Hosp,Univ Chinese Acad Sci, Zhejiang Canc Hosp, Inst Canc & Basic Med IBMC,Dept Canc Prevent, Hangzhou, Peoples R China 4.Chinese Acad Med Sci & Peking Union Med Coll, Canc Hosp, Natl Canc Ctr, Natl Clin Res Ctr Canc,Natl Cent Canc Registry, 17 South Panjiayuan Lane, Beijing 100021, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Juan,Ma, Shanrui,Chen, Ru,et al. Long-term anxiety and depression signatures of participants that received esophageal cancer screening: A multicenter population-based cohort study[J]. CANCER MEDICINE,2022:13. |
| APA | Zhu, Juan.,Ma, Shanrui.,Chen, Ru.,Xie, Shuanghua.,Liu, Zhaorui.,...&Wei, Wenqiang.(2022).Long-term anxiety and depression signatures of participants that received esophageal cancer screening: A multicenter population-based cohort study.CANCER MEDICINE,13. |
| MLA | Zhu, Juan,et al."Long-term anxiety and depression signatures of participants that received esophageal cancer screening: A multicenter population-based cohort study".CANCER MEDICINE (2022):13. |
入库方式： OAI收割
来源：心理研究所
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