中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A self-assembled polydopamine film on the surface of magnetic nanoparticles for specific capture of protein

文献类型:期刊论文

作者Zhang, Min1,2; Zhang, Xihao1,2; He, Xiwen1,2; Chen, Langxing1,2; Zhang, Yukui1,2,3
刊名nanoscale
出版日期2012
卷号4期号:10页码:3141-3147
产权排序3,5
通讯作者陈朗星
英文摘要in this study, we report a facile method for the preparation of core-shell magnetic molecularly imprinted polymers (mips) for protein recognition. uniform carboxyl group functionalized fe3o4 nanoparticles (nps) were synthesized using a solvothermal method. magnetic mips were synthesized by self-polymerization of dopamine in the presence of template protein on the surface of the fe3o4 nps. a thin layer of polydopamine can be coated on fe3o4 nps via dopamine self-polymerization and the imprinted polydopamine shells can be controlled by the mass ratio of fe3o4 nps and dopamine. more importantly, there is a critical value of polydopamine shell thickness for the maximum rebinding capacity. the as-prepared lysozyme-imprinted fe3o4@polydopamine nps show high binding capacity and acceptable specific recognition behavior towards template proteins. this method provides the possibility for the separation and enrichment of abundant proteins in proteomic analysis.
WOS标题词science & technology ; physical sciences ; technology
学科主题物理化学
类目[WOS]chemistry, multidisciplinary ; nanoscience & nanotechnology ; materials science, multidisciplinary ; physics, applied
研究领域[WOS]chemistry ; science & technology - other topics ; materials science ; physics
关键词[WOS]molecularly imprinted polymers ; histidine-tagged proteins ; iron-oxide nanoparticles ; bovine hemoglobin ; biomedical applications ; sorbent assays ; aqueous-media ; human serum ; recognition ; shell
收录类别SCI
语种英语
WOS记录号WOS:000303604000024
公开日期2013-10-11
源URL[http://159.226.238.44/handle/321008/118171]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.Nankai Univ, State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China
2.Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China
3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116011, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Min,Zhang, Xihao,He, Xiwen,et al. A self-assembled polydopamine film on the surface of magnetic nanoparticles for specific capture of protein[J]. nanoscale,2012,4(10):3141-3147.
APA Zhang, Min,Zhang, Xihao,He, Xiwen,Chen, Langxing,&Zhang, Yukui.(2012).A self-assembled polydopamine film on the surface of magnetic nanoparticles for specific capture of protein.nanoscale,4(10),3141-3147.
MLA Zhang, Min,et al."A self-assembled polydopamine film on the surface of magnetic nanoparticles for specific capture of protein".nanoscale 4.10(2012):3141-3147.

入库方式: OAI收割

来源:大连化学物理研究所

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