Protein-imprinted materials: rational design, application and challenges
文献类型：期刊论文
| 作者 | Yang, Kaiguang; Zhang, Lihua; Liang, Zhen; Zhang, Yukui |
| 刊名 | analytical and bioanalytical chemistry
 |
| 出版日期 | 2012-06-01 |
| 卷号 | 403期号:8页码:2173-2183 |
| 关键词 | Molecular imprinting Protein Antibody Recognition sites |
| 产权排序 | 1,1 |
| 通讯作者 | 张丽华 |
| 英文摘要 | protein imprinting is a promising tool for generating artificial biomimetic receptors with antibody-like specific recognition sites. recently, protein-imprinted materials, as potential antibody substitutes, have attracted much attention in many fields, for example chemical sensors, chromatographic stationary phases, and artificial enzymes, owing to their long-term storage stability, potential re-usability, resistance to harsh environment, and low cost. in this critical review, we focus our discussion on the rational preparation of protein-imprinted materials in terms of choice of template, functional monomer, crosslinker, and polymerization format. in addition, several highlighted applications of protein-imprinted materials are emphasized, not only in well-known fields but also in some unique fields, for example proteomics and tissue engineering. finally, we propose challenges arising from the intrinsic properties of protein imprinting, for example obtaining the template, heterogeneous binding, and extrinsic competition, for example immobilized aptamers. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 学科主题 | 物理化学 |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | unique electrophoresis technique ; minute structural differences ; artificial gel antibodies ; capillary-electrophoresis ; epitope approach ; liquid-chromatography ; universal method ; aqueous-media ; recognition ; polymers |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000305127200010 |
| 公开日期 | 2013-10-11 |
| 源URL | [http://159.226.238.44/handle/321008/118174]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Kaiguang,Zhang, Lihua,Liang, Zhen,et al. Protein-imprinted materials: rational design, application and challenges[J]. analytical and bioanalytical chemistry,2012,403(8):2173-2183. |
| APA | Yang, Kaiguang,Zhang, Lihua,Liang, Zhen,&Zhang, Yukui.(2012).Protein-imprinted materials: rational design, application and challenges.analytical and bioanalytical chemistry,403(8),2173-2183. |
| MLA | Yang, Kaiguang,et al."Protein-imprinted materials: rational design, application and challenges".analytical and bioanalytical chemistry 403.8(2012):2173-2183. |
入库方式： OAI收割
来源：大连化学物理研究所
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