Improvement of peptoid chiral stationary phases by modifying the terminal group of selector
文献类型：期刊论文
| 作者 | Wu, Haibo1; Su, Xiaobing1; Li, Kuiyong1; Yu, Hui1; Ke, Yanxiong1; Liang, Xinmiao1,2 |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2012-11-23 |
| 卷号 | 1265页码:181-185 |
| 关键词 | Peptoid Oligopeptoid Chiral stationary phase Chiral separation |
| 产权排序 | 2,6 |
| 通讯作者 | 梁鑫淼 ; 柯燕雄 |
| 英文摘要 | the role of a terminal group of a peptoid selector in a chiral separation was investigated. six chiral stationary phases (csps) with the terminal groups replaced by achiral alkyl groups (n-butyl, t-butyl and diisopropyl) and chiral groups ((1r, 2r)-2-aminocyclohexyl phenylcarbamate, n'-phenyl-l-proline amide and n'-phenyl-l-leucine amide) were synthesized. achiral terminal groups with different steric hindrances did not broaden the enantioselectivity, but improved the separation factors for some analytes, probably due to the improvement of interactions between the analytes and peptoid chain. introducing new chiral terminal groups proved an effective way to broaden the applicable spectrum of peptoid csps. (c) 2012 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 学科主题 | 物理化学 |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | enantiomeric separations ; liquid-chromatography ; performance ; columns ; hplc |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000311011000022 |
| 公开日期 | 2013-10-11 |
| 源URL | [http://159.226.238.44/handle/321008/118177]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.E China Univ Sci & Technol, Sch Pharm, Minist Educ, Engn Res Ctr Pharmaceut Proc Chem, Shanghai 200237, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Haibo,Su, Xiaobing,Li, Kuiyong,et al. Improvement of peptoid chiral stationary phases by modifying the terminal group of selector[J]. journal of chromatography a,2012,1265:181-185. |
| APA | Wu, Haibo,Su, Xiaobing,Li, Kuiyong,Yu, Hui,Ke, Yanxiong,&Liang, Xinmiao.(2012).Improvement of peptoid chiral stationary phases by modifying the terminal group of selector.journal of chromatography a,1265,181-185. |
| MLA | Wu, Haibo,et al."Improvement of peptoid chiral stationary phases by modifying the terminal group of selector".journal of chromatography a 1265(2012):181-185. |
入库方式： OAI收割
来源：大连化学物理研究所
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