Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: From qualitative to quantitative analysis-A review
文献类型:期刊论文
作者 | Wu, Qi1,2; Yuan, Huiming1; Zhang, Lihua1; Zhang, Yukui1 |
刊名 | analytica chimica acta
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出版日期 | 2012-06-20 |
卷号 | 731页码:1-10 |
关键词 | Multidimensional liquid chromatography Qualitative analysis Quantitative analysis Proteomics |
产权排序 | 1,1 |
通讯作者 | 张丽华 |
英文摘要 | with the acceleration of proteome research, increasing attention has been paid to multidimensional liquid chromatography-mass spectrometry (mdlc-ms) clue to its high peak capacity and separation efficiency. recently, many efforts have been put to improve mdlc-based strategies including "top-down" and "bottom-up" to enable highly sensitive qualitative and quantitative analysis of proteins, as well as accelerate the whole analytical procedure. integrated platforms with combination of sample pretreatment, multidimensional separations and identification were also developed to achieve high throughput and sensitive detection of proteomes, facilitating highly accurate and reproducible quantification. this review summarized the recent advances of such techniques and their applications in qualitative and quantitative analysis of proteomes. (c) 2012 elsevier b.v. all rights reserved. |
WOS标题词 | science & technology ; physical sciences |
学科主题 | 物理化学 |
类目[WOS] | chemistry, analytical |
研究领域[WOS] | chemistry |
关键词[WOS] | complex protein mixtures ; strong cation-exchange ; coded affinity tags ; label-free ; lc-ms/ms ; membrane-proteins ; peak-capacity ; saccharomyces-cerevisiae ; amino-acids ; maldi-tof |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000305380600001 |
公开日期 | 2013-10-11 |
源URL | [http://159.226.238.44/handle/321008/118305] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Wu, Qi,Yuan, Huiming,Zhang, Lihua,et al. Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: From qualitative to quantitative analysis-A review[J]. analytica chimica acta,2012,731:1-10. |
APA | Wu, Qi,Yuan, Huiming,Zhang, Lihua,&Zhang, Yukui.(2012).Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: From qualitative to quantitative analysis-A review.analytica chimica acta,731,1-10. |
MLA | Wu, Qi,et al."Recent advances on multidimensional liquid chromatography-mass spectrometry for proteomics: From qualitative to quantitative analysis-A review".analytica chimica acta 731(2012):1-10. |
入库方式: OAI收割
来源:大连化学物理研究所
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