The Complex of Phycobiliproteins, Fucoxanthin, and Krill Oil Ameliorates Obesity through Modulation of Lipid Metabolism and Antioxidants in Obese Rats
文献类型：期刊论文
| 作者 | Qiang, Xi1,2,3; Guo, Chuanlong4; Gu, Wenhui1,5; Song, Yuling1; Zhang, Yuhong6; Gong, Xiangzhong2; Wang, Lijun1,3,5; Wang, Guangce1,5 |
| 刊名 | NUTRIENTS
 |
| 出版日期 | 2022-11-01 |
| 卷号 | 14期号:22页码:12 |
| 关键词 | obesity lipid metabolism phycobiliproteins fucoxanthin krill oil |
| DOI | 10.3390/nu14224815 |
| 通讯作者 | Wang, Lijun(wanglijun@qdio.ac.cn) ; Wang, Guangce(gcwang@qdio.ac.cn) |
| 英文摘要 | Phycobiliproteins, fucoxanthin, and krill oil are natural marine products with excellent activities. In the study, we prepared the complex of phycobiliproteins, fucoxanthin, and krill oil (PFK) and assessed the anti-obesity, lipid-lowering, and antioxidant activities in high-fat diet rats. The results showed that the rats significantly and safely reduced body weight gain and regulated serum biochemical parameters at 50 mg/kg phycobiliproteins, 10 mg/kg fucoxanthin, and 100 mg/kg krill oil. Furthermore, the molecular mechanism study suggested that the complex of PFK confined the enzyme activities of lipid synthesis and enhanced antioxidant activity to improve obesity indirectly. The conclusions demonstrated that the complex of PFK has potent anti-obesity and hypolipidemic effects which have potential use as a natural and healthy food and medicine for anti-obesity and lowering blood lipids in the future. |
| 资助项目 | Major Scientific and Technological Innovation Projects of Shandong Province[2019JZZY010815] ; National Key R&D Program of China[2018YFD0901500] ; Ministry of Agriculture and Rural Affairs of the People's Republic of China[CARS-50] ; Nantong Municipal Science and Technology Planning Project[MS22021017] ; Research Fund for the Taishan Scholar Project of Shandong Province[tspd 20210316] |
| WOS研究方向 | Nutrition & Dietetics |
| 语种 | 英语 |
| 出版者 | MDPI |
| WOS记录号 | WOS:000887567700001 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/180268]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Wang, Lijun; Wang, Guangce |
| 作者单位 | 1.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Ocean Univ China, Coll Marine Life Sci, Qingdao 266003, Peoples R China 3.Nantong Zhong Ke Marine Sci & Technol R&D Ctr, Nantong 226334, Peoples R China 4.Qingdao Univ Sci & Technol, Coll Chem Engn, Dept Pharm, Qingdao 266042, Peoples R China 5.Pilot Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China 6.Qingdao Shinan Dist Ctr Dis Control & Prevent, Qingdao 266072, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiang, Xi,Guo, Chuanlong,Gu, Wenhui,et al. The Complex of Phycobiliproteins, Fucoxanthin, and Krill Oil Ameliorates Obesity through Modulation of Lipid Metabolism and Antioxidants in Obese Rats[J]. NUTRIENTS,2022,14(22):12. |
| APA | Qiang, Xi.,Guo, Chuanlong.,Gu, Wenhui.,Song, Yuling.,Zhang, Yuhong.,...&Wang, Guangce.(2022).The Complex of Phycobiliproteins, Fucoxanthin, and Krill Oil Ameliorates Obesity through Modulation of Lipid Metabolism and Antioxidants in Obese Rats.NUTRIENTS,14(22),12. |
| MLA | Qiang, Xi,et al."The Complex of Phycobiliproteins, Fucoxanthin, and Krill Oil Ameliorates Obesity through Modulation of Lipid Metabolism and Antioxidants in Obese Rats".NUTRIENTS 14.22(2022):12. |
入库方式： OAI收割
来源：海洋研究所
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