Enantiomeric pairs of meroterpenoids with 11/5/6 spiro-heterocyclic systems from Hypericum kouytchense
文献类型：期刊论文
| 作者 | Huang, Jin-Chang2,3; Sheng, Li1; Zong, Jian-Fa2; Zhou, Yu-Bo1 ; Li, Jia1; Hou, Ai-Jun2,3
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| 刊名 | ORGANIC CHEMISTRY FRONTIERS
 |
| 出版日期 | 2022-10-25 |
| 页码 | 9 |
| ISSN号 | 2052-4129 |
| DOI | 10.1039/d2qo01485h |
| 通讯作者 | Hou, Ai-Jun(ajhou@sjtu.edu.cn) |
| 英文摘要 | Six undescribed enantiomeric pairs of acylphloroglucinol related meroterpenoids, (+/-)-hyperkouytins A-F (1a/1b-6a/6b), were isolated from Hypericum kouytchense. These enantiomers were acquired by chiral-phase HPLC, and their structures were established using spectroscopic and X-ray crystallographic data. These compounds incorporate a rare 11/5/6 heterocyclic system featuring a 1-oxaspiro[4.10]pentadecane moiety. Compounds 1b and 3a exerted antiproliferation activity against the MV-4-11 cell line. |
| WOS关键词 | CHEMISTRY |
| 资助项目 | National Natural Science Foundation of China[22277074] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000877071700001 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/303020]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Hou, Ai-Jun |
| 作者单位 | 1.Chinese Acad Sci, Natl Ctr Drug Screening, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Fudan Univ, Sch Pharm, Shanghai 201203, Peoples R China 3.Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Jin-Chang,Sheng, Li,Zong, Jian-Fa,et al. Enantiomeric pairs of meroterpenoids with 11/5/6 spiro-heterocyclic systems from Hypericum kouytchense[J]. ORGANIC CHEMISTRY FRONTIERS,2022:9. |
| APA | Huang, Jin-Chang,Sheng, Li,Zong, Jian-Fa,Zhou, Yu-Bo,Li, Jia,&Hou, Ai-Jun.(2022).Enantiomeric pairs of meroterpenoids with 11/5/6 spiro-heterocyclic systems from Hypericum kouytchense.ORGANIC CHEMISTRY FRONTIERS,9. |
| MLA | Huang, Jin-Chang,et al."Enantiomeric pairs of meroterpenoids with 11/5/6 spiro-heterocyclic systems from Hypericum kouytchense".ORGANIC CHEMISTRY FRONTIERS (2022):9. |
入库方式： OAI收割
来源：上海药物研究所
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