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Polyoxygenated cembranoids from the South China Sea soft coral Sarcophyton boettgeri and their stereochemistry

文献类型：期刊论文

作者Liu, Jiao4,5; Xu, Ting4; Yao, Li-Gong; Li, Song-Wei3; Guo, Yue-Wei1,2,4,5
刊名FITOTERAPIA
出版日期2022-10-01
卷号162页码:7
ISSN号0367-326X
关键词Soft coral Sarcophyton boettgeri Cembranoid Absolute configuration
DOI10.1016/j.fitote.2022.105299
通讯作者Li, Song-Wei(songweili93@zjut.edu.cn) ; Guo, Yue-Wei(ywguo@simm.ac.cn)
英文摘要Four new polyoxygenated cembranoids, namely sarcoboettgerol A (1), 12-epi-humilisin D (2), sarcoboettgerol B (3), and sarcoboettgerol C (4), together with one known related analogue, humilisin D (5), were isolated and characterized from the soft coral Sarcophyton boettgeri collected off Ximao island, Hainan Province, China. The structures and absolute configurations of the new compounds were determined by extensive spectroscopic data analyses, Cu k alpha single crystal X-ray diffraction analysis, and TDDFT-ECD calculations. A plausible biogenetic relationship of 3 and 4 was proposed.
WOS关键词DITERPENOIDS ; TROCHELIOPHORUM ; STEROIDS
资助项目National Nat- ural Science Foundation of China ; SKLDR/SIMM Project ; [81991521] ; [SIMM2103ZZ-06]
WOS研究方向Pharmacology & Pharmacy
语种英语
出版者ELSEVIER
WOS记录号WOS:000870866700011
源URL[http://119.78.100.183/handle/2S10ELR8/303220]  
专题新药研究国家重点实验室
通讯作者Li, Song-Wei; Guo, Yue-Wei
作者单位1.Pilot Natl Lab Marine Sci & Technol Qingdao, Open Studio Druggabil Res Marine Nat Prod, 1 Wenhai Rd, Qingdao 266237, Peoples R China
2.Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai 264117, Shandong, Peoples R China
3.Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Peoples R China
4.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China
5.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China
推荐引用方式
GB/T 7714		 Liu, Jiao,Xu, Ting,Yao, Li-Gong,et al. Polyoxygenated cembranoids from the South China Sea soft coral Sarcophyton boettgeri and their stereochemistry[J]. FITOTERAPIA,2022,162:7.
APA Liu, Jiao,Xu, Ting,Yao, Li-Gong,Li, Song-Wei,&Guo, Yue-Wei.(2022).Polyoxygenated cembranoids from the South China Sea soft coral Sarcophyton boettgeri and their stereochemistry.FITOTERAPIA,162,7.
MLA Liu, Jiao,et al."Polyoxygenated cembranoids from the South China Sea soft coral Sarcophyton boettgeri and their stereochemistry".FITOTERAPIA 162(2022):7.

入库方式： OAI收割

来源：上海药物研究所

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