Preparation of l-Arginine Schiff Bases Modified Chitosan Derivatives and Their Antimicrobial and Antioxidant Properties
文献类型：期刊论文
| 作者 | Cui, Jingmin2,3,4; Sun, Yan2,3,4; Wang, Linqing1; Miao, Qin2,3,4; Tan, Wenqiang2,4 ; Guo, Zhanyong2,3,4
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| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2022-11-01 |
| 卷号 | 20期号:11页码:16 |
| 关键词 | chitosan l-arginine Schiff bases heterocyclic compounds |
| DOI | 10.3390/md20110688 |
| 英文摘要 | We successfully prepared a series of l-arginine Schiff bases acylated chitosan derivatives, aiming to improve the antioxidant activity and antimicrobial activity of chitosan by introducing a furan ring, pyridine ring, and l-arginine structure. The accuracy of the structures of ten compounds was characterized by FT-IR and H-1 NMR. In terms of DPPH radical scavenging activity, except for compound CR3PCA, the scavenging rate of other compounds was higher than chitosan, especially CRCF and CRBF had strong scavenging abilities. At the same time, in the superoxide-radical scavenging activity assay, CRCF, CRBF, CR3PCA, CR2C3PCA, and CR2B3PCA were comparable to positive control at 1.60 mg/mL. Simultaneously, CRFF, CRCF, and CRBF had a certain inhibitory effect on Botrytis cinerea. Furthermore, the inhibitory effect of CRFF, CRCF, and CR3PCA on Staphylococcus aureus was very well, close to the positive control at 1.00 mg/mL. CRCF and CR2B3PCA showed better inhibitory effects on Escherichia coli than other compounds. The MTT assay was used to determine the cytotoxicity of the chitosan derivatives, which proved their safety to fibroblast cells. In summary, the study indicated that some of these compounds have the potential for further development and utilization in the preparation of antioxidants and antimicrobial agents. |
| WOS关键词 | AMINO-ACIDS ; ANTIBACTERIAL ; COMPLEXES ; MODE ; COPPER(II) ; PLANT |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000895550000001 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/31888]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物资源高效利用研究与发展中心 |
| 通讯作者 | Guo, Zhanyong |
| 作者单位 | 1.Ludong Univ, Sch Chem & Mat Sci, Yantai 264025, Peoples R China 2.Chinese Acad Sci, Ctr Oceanmega Sci, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cui, Jingmin,Sun, Yan,Wang, Linqing,et al. Preparation of l-Arginine Schiff Bases Modified Chitosan Derivatives and Their Antimicrobial and Antioxidant Properties[J]. MARINE DRUGS,2022,20(11):16. |
| APA | Cui, Jingmin,Sun, Yan,Wang, Linqing,Miao, Qin,Tan, Wenqiang,&Guo, Zhanyong.(2022).Preparation of l-Arginine Schiff Bases Modified Chitosan Derivatives and Their Antimicrobial and Antioxidant Properties.MARINE DRUGS,20(11),16. |
| MLA | Cui, Jingmin,et al."Preparation of l-Arginine Schiff Bases Modified Chitosan Derivatives and Their Antimicrobial and Antioxidant Properties".MARINE DRUGS 20.11(2022):16. |
入库方式： OAI收割
来源：烟台海岸带研究所
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