Genome-Wide Identification of Laminin Family Related to Follicular Pseudoplacenta Development in Black Rockfish (Sebastes schlegelii)
文献类型：期刊论文
| 作者 | Zhao, Ning2,3,4,5; Wang, Xueying3,4,5 ; Wang, Tao1,3,4,5; Xu, Xiaojie2,3,4,5; Liu, Qinghua3,4,5; Li, Jun3,4,5
|
| 刊名 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
 |
| 出版日期 | 2022-09-01 |
| 卷号 | 23期号:18页码:12 |
| 关键词 | Sebastes schlegelii follicular pseudoplacenta laminin genes evolution |
| DOI | 10.3390/ijms231810523 |
| 通讯作者 | Liu, Qinghua(qinghualiu@qdio.ac.cn) ; Li, Jun(junli@qdio.ac.cn) |
| 英文摘要 | As major elements of the basement membrane, laminins play a significant role in angiogenesis, migration, and adhesion of various cells. Sebastes schlegelii is a marine viviparous teleost of commercial importance. Previous research has reported abundant blood vessels and connective tissue in the ovary during gestation. In this study, 14 laminin genes of the alpha, beta, and gamma subfamilies from genomic data were identified based on zebrafish and human laminins, distributed on 9 chromosomes in S. schlegelii. Analysis of structural domains showed that coiled-coil regions and EGF domains existed in all laminin genes. Moreover, via qPCR, we found that the expression of laminin genes, including lama4, lama5, lamb4, lamc1, and lamc3, gradually increased from the phase III ovary stage and peaked in the early stage of gestation, especially lama4 and lama5 which showed dramatically increased expression at the blastula stage. Accordingly, in situ hybridization of lama4 was conducted. The results revealed that signals became stronger following the phase IV ovary stage, and the strongest signals were located on the follicular pseudoplacenta at the blastula stage. These results suggest that the high expression of laminin genes, especially lama4 after fertilization, may drive cell proliferation, migration, and tissue expansion in the S. schlegelii ovary and ultimately promote follicular pseudoplacenta formation. |
| 资助项目 | National Key Research and Development Program of China[2018YFD0901205] ; National Key Research and Development Program of China[2018YFD0901204] ; Research and Development Program of Shandong Province[2021LZGC029] ; Shandong Province Natural Science Foundation[ZR2020KC038] ; China Agriculture Research System[CARS-47] ; National Marine Genetic Resource Center |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000857500700001 |
| 出版者 | MDPI |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/180777]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Liu, Qinghua; Li, Jun |
| 作者单位 | 1.Qingdao Agr Univ, Sch Marine Sci & Engn, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 5.Chinese Acad Sci, Ctr Ocean Megasci, Inst Oceanol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Ning,Wang, Xueying,Wang, Tao,et al. Genome-Wide Identification of Laminin Family Related to Follicular Pseudoplacenta Development in Black Rockfish (Sebastes schlegelii)[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2022,23(18):12. |
| APA | Zhao, Ning,Wang, Xueying,Wang, Tao,Xu, Xiaojie,Liu, Qinghua,&Li, Jun.(2022).Genome-Wide Identification of Laminin Family Related to Follicular Pseudoplacenta Development in Black Rockfish (Sebastes schlegelii).INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,23(18),12. |
| MLA | Zhao, Ning,et al."Genome-Wide Identification of Laminin Family Related to Follicular Pseudoplacenta Development in Black Rockfish (Sebastes schlegelii)".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23.18(2022):12. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。