Aromatic Polyketides from the Deep-Sea Cold-Seep Mussel Associated Endozoic Fungus Talaromyces minioluteus CS-138
文献类型：期刊论文
| 作者 | Song, Qi2,3,4 ; Yang, Sui-Qun1,3,4; Li, Xiao-Ming1,3,4; Hu, Xue-Yi2,3,4; Li, Xin1,3,4; Wang, Bin-Gui1,2,3,4
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| 刊名 | MARINE DRUGS
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| 出版日期 | 2022-08-01 |
| 卷号 | 20期号:8页码:9 |
| 关键词 | Talaromyces minioluteus Gigantidas platifrons deep-sea cold seep antimicrobial activity DPPH scavenging activity |
| DOI | 10.3390/md20080529 |
| 通讯作者 | Wang, Bin-Gui(wangbg@ms.qdio.ac.cn) |
| 英文摘要 | Five new aromatic polyketides, including a unique benzofuran derivative, talarominine A (1), and four chromone analogs talamins A-D (2-5), along with one known related metabolite, 5-hydroxy-7-methoxy-2,3-dimethylchromone (6), were isolated and identified from the Talaromyces minioluteus CS-138, an endozoic fungus obtained from the deep-sea cold seep mussel Gigantidas platifrons. Their chemical structures were elucidated by detailed analysis of their NMR spectra, HRESIMS and X-ray crystallographic data, and by comparison with literature data as well. The antibacterial and DPPH scavenging activities of compounds 1-6 were evaluated. Compounds 1-3 showed inhibitory activity against some of the tested bacteria whereas compounds 2 and 5 showed potent DPPH radical scavenging activities, which were better than that of the positive control butylated hydroxytoluene (BHT). This work is likely the first report on marine natural products of mussel-derived fungus living in cold seep environments. |
| 资助项目 | Strategic Priority Research Program of Chinese Academy of Sciences[XDA22050401] ; National Natural Science Foundation of China[U2006203] ; National Natural Science Foundation of China[82003648] ; National Natural Science Foundation of China[KEXUE2020GZ02] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000845475300001 |
| 出版者 | MDPI |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/180852]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Wang, Bin-Gui |
| 作者单位 | 1.Chinese Acad Sci, Ctr Ocean Mega Sci, Nanhai Rd 7, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Coll Marine Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Song, Qi,Yang, Sui-Qun,Li, Xiao-Ming,et al. Aromatic Polyketides from the Deep-Sea Cold-Seep Mussel Associated Endozoic Fungus Talaromyces minioluteus CS-138[J]. MARINE DRUGS,2022,20(8):9. |
| APA | Song, Qi,Yang, Sui-Qun,Li, Xiao-Ming,Hu, Xue-Yi,Li, Xin,&Wang, Bin-Gui.(2022).Aromatic Polyketides from the Deep-Sea Cold-Seep Mussel Associated Endozoic Fungus Talaromyces minioluteus CS-138.MARINE DRUGS,20(8),9. |
| MLA | Song, Qi,et al."Aromatic Polyketides from the Deep-Sea Cold-Seep Mussel Associated Endozoic Fungus Talaromyces minioluteus CS-138".MARINE DRUGS 20.8(2022):9. |
入库方式： OAI收割
来源：海洋研究所
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