Defective mitochondrial function by mutation in THICK ALEURONE 1 encoding a mitochon-driontargeted single-stranded DNA-binding protein leads to increased aleurone cell layers and improved nutrition in rice
文献类型：期刊论文
| 作者 | Li, Dong-Qi; Wu, Xiao-Ba; Wang, Hai-Feng; Feng, Xue; Yan, Shi-Juan; Wu, Sheng-Yang; Liu, Jin-Xin; Yao, Xue-Feng; Bai, Ai-Ning; Zhao, Heng |
| 刊名 | MOLECULAR PLANT
 |
| 出版日期 | 2021 |
| 卷号 | 14期号:8页码:1343-1361 |
| ISSN号 | 1674-2052 |
| 关键词 | rice thick aleurone cell-fate determination nutritional improvement mitochondria |
| DOI | 10.1016/j.molp.2021.05.016 |
| 文献子类 | Article |
| 英文摘要 | Cereal endosperm comprises an outer aleurone and an inner starchy endosperm. Although these two tissues have the same developmental origin, they differ in morphology, cell fate, and storage product accumulation, with the mechanism largely unknown. Here, we report the identification and characterization of rice thick aleurone 1 (ta1) mutant that shows an increased number of aleurone cell layers and increased contents of nutritional factors including proteins, lipids, vitamins, dietary fibers, and micronutrients. We identified that the TA1 gene, which is expressed in embryo, aleurone, and subaleurone in caryopses, encodes a mitochondrion-targeted protein with single-stranded DNA-binding activity named OsmtSSB1. Cytological analyses revealed that the increased aleurone cell layers in ta1 originate from a developmental switch of subaleurone toward aleurone instead of starchy endosperm in the wild type. We found that TA1/OsmtSSB1 interacts with mitochondrial DNA recombinase RECA3 and DNA helicase TWINKLE, and down-regulation of RECA3 or TWINKLE also leads to ta1-like phenotypes. We further showed that mutation in TA1/OsmtSSB1 causes elevated illegitimate recombinations in the mitochondrial genome, altered mitochondrial morphology, and compromised energy supply, suggesting that the OsmtSSB1-mediated mitochondrial function plays a critical role in subaleurone cell-fate determination in rice. |
| 学科主题 | Biochemistry & Molecular Biology ; Plant Sciences |
| 电子版国际标准刊号 | 1752-9867 |
| 出版地 | CAMBRIDGE |
| WOS关键词 | ORYZA-SATIVA-L ; MAIZE ENDOSPERM ; TRANSCRIPTION FACTORS ; ALTERNATIVE OXIDASE ; EXPRESSION ANALYSIS ; MOLECULAR-CLONING ; GENE-EXPRESSION ; DYNAMIC CHANGES ; OPAQUE-2 MAIZE ; CARYOPSIS |
| WOS研究方向 | Science Citation Index Expanded (SCI-EXPANDED) |
| 语种 | 英语 |
| 出版者 | CELL PRESS |
| WOS记录号 | WOS:000681059100019 |
| 资助机构 | Chinese Academy of Sciences Innovation Project Molecular Modules for Breeding Design'' [XDA24010402] ; Beijing Municipal Science and Technology Commission Project [Z181100002418010] ; CAS-CSIRO Bilateral Collaboration Project [151111KYSB20180049] |
| 源URL | [http://ir.ibcas.ac.cn/handle/2S10CLM1/26335]  |
| 专题 | 中科院植物分子生理学重点实验室 |
| 作者单位 | 1.Feng, Xue 2.Wu, Xiao-Ba 3.[Li, Dong-Qi 4.Wu, Sheng-Yang 5.Chinese Acad Sci, Innovat Acad Seed Design, Beijing 100101, Peoples R China 6.Peking Univ, Sch Adv Agr Sci, Beijing 100871, Peoples R China 7.Chinese Acad Agr Sci, Inst Crop Sci, Beijing 100081, Peoples R China 8.Guo, Lin 9.[Zhao, Heng 10.Guangdong Acad Agr Sci, Agrobiol Gene Res Ctr, Guangdong Key Lab Crop Germplasm Resources Preser, Guangzhou 510640, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Dong-Qi,Wu, Xiao-Ba,Wang, Hai-Feng,et al. Defective mitochondrial function by mutation in THICK ALEURONE 1 encoding a mitochon-driontargeted single-stranded DNA-binding protein leads to increased aleurone cell layers and improved nutrition in rice[J]. MOLECULAR PLANT,2021,14(8):1343-1361. |
| APA | Li, Dong-Qi.,Wu, Xiao-Ba.,Wang, Hai-Feng.,Feng, Xue.,Yan, Shi-Juan.,...&Liu, Chun-Ming.(2021).Defective mitochondrial function by mutation in THICK ALEURONE 1 encoding a mitochon-driontargeted single-stranded DNA-binding protein leads to increased aleurone cell layers and improved nutrition in rice.MOLECULAR PLANT,14(8),1343-1361. |
| MLA | Li, Dong-Qi,et al."Defective mitochondrial function by mutation in THICK ALEURONE 1 encoding a mitochon-driontargeted single-stranded DNA-binding protein leads to increased aleurone cell layers and improved nutrition in rice".MOLECULAR PLANT 14.8(2021):1343-1361. |
入库方式： OAI收割
来源：植物研究所
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