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Mapping causal genes and genetic interactions for agronomic traits using a large F-2 population in rice

文献类型：期刊论文

作者Feng, Laibao1,2; Ma, Aimin1; Song, Bo1; Yu, Sibin4; Qi, Xiaoquan1
刊名G3-GENES GENOMES GENETICS
出版日期2021
卷号11期号:11
关键词quantitative trait loci large F-2 population rice causal gene genetic interactions
ISSN号2160-1836
DOI10.1093/g3journal/jkab318
文献子类Article
英文摘要Dissecting the genetic mechanisms underlying agronomic traits is of great importance for crop breeding. Agronomic traits are usually controlled by multiple quantitative trait loci (QTLs) and genetic interactions, and mapping the underlying causal genes is still labor-intensive and time-consuming. Here, we present a genetic tool for directly targeting the specific causal genes by using a single-gene resolution linkage map that was constructed from 3756 F-2 rice plants via targeted sequencing technology and Tukey-Kramer multiple comparisons test. Three large- and moderate-effect QTLs, qHD6-2, qGL3-1, and qGW5-2, were successfully mapped to their specific causal genes, Hd1, GS3, and GW5, respectively. A complex genetic interaction network containing 30 QTL-QTL interactions was constructed, revealing that the alternative allele of hub QTL, qHD6-2, can hide or release the genetic contributions of the alleles at interacting loci. Moreover, arranging genetic interactions in the models lead to more accurate phenotypic predictions. These results provide a community resource and new feasible strategy for deciphering the genetic mechanisms of complex agronomic traits and accelerating crop breeding.
学科主题Genetics & Heredity
出版地CARY
WOS关键词GENOME-WIDE ASSOCIATION ; NATURAL VARIATION ; READ ALIGNMENT ; FLOWERING TIME ; GRAIN LENGTH ; REVEALS ; HETEROSIS ; PROTEIN ; IDENTIFICATION ; EPISTASIS
WOS研究方向Science Citation Index Expanded (SCI-EXPANDED)
语种英语
WOS记录号WOS:000735905700043
出版者OXFORD UNIV PRESS INC
资助机构National Transgenic Megaproject of China [2016ZX08009001-006] ; Strategic Priority Research Program of the Chinese Academy of Sciences [XDB27010202] ; Nation Key Research and Development Program of China [2016YFD0100904]
源URL[http://ir.ibcas.ac.cn/handle/2S10CLM1/26739]  
专题中科院植物分子生理学重点实验室
作者单位1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
2.Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China
3.Huazhong Agr Univ, Coll Plant Sci & Technol, Natl Key Lab Crop Genet Improvement, Wuhan 430070, Hubei, Peoples R China
4.Chinese Acad Sci, Innovat Acad Seed Design, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Feng, Laibao,Ma, Aimin,Song, Bo,et al. Mapping causal genes and genetic interactions for agronomic traits using a large F-2 population in rice[J]. G3-GENES GENOMES GENETICS,2021,11(11).
APA Feng, Laibao,Ma, Aimin,Song, Bo,Yu, Sibin,&Qi, Xiaoquan.(2021).Mapping causal genes and genetic interactions for agronomic traits using a large F-2 population in rice.G3-GENES GENOMES GENETICS,11(11).
MLA Feng, Laibao,et al."Mapping causal genes and genetic interactions for agronomic traits using a large F-2 population in rice".G3-GENES GENOMES GENETICS 11.11(2021).

入库方式： OAI收割

来源：植物研究所

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