The Chloroplast Epitranscriptome: Factors, Sites, Regulation, and Detection Methods
文献类型：期刊论文
| 作者 | Manavski, Nikolay; Vicente, Alexandre; Chi, Wei2; Meurer, Jorg |
| 刊名 | GENES
 |
| 出版日期 | 2021 |
| 卷号 | 12期号:8 |
| 关键词 | chloroplast RNA metabolism epitranscriptome RNA methylation posttranscriptional regulation development acclimation stress response |
| DOI | 10.3390/genes12081121 |
| 文献子类 | Review |
| 英文摘要 | Modifications in nucleic acids are present in all three domains of life. More than 170 distinct chemical modifications have been reported in cellular RNAs to date. Collectively termed as epitranscriptome, these RNA modifications are often dynamic and involve distinct regulatory proteins that install, remove, and interpret these marks in a site-specific manner. Covalent nucleotide modifications-such as methylations at diverse positions in the bases, polyuridylation, and pseudouridylation and many others impact various events in the lifecycle of an RNA such as folding, localization, processing, stability, ribosome assembly, and translational processes and are thus crucial regulators of the RNA metabolism. In plants, the nuclear/cytoplasmic epitranscriptome plays important roles in a wide range of biological processes, such as organ development, viral infection, and physiological means. Notably, recent transcriptome-wide analyses have also revealed novel dynamic modifications not only in plant nuclear/cytoplasmic RNAs related to photosynthesis but especially in chloroplast mRNAs, suggesting important and hitherto undefined regulatory steps in plastid functions and gene expression. Here we report on the latest findings of known plastid RNA modifications and highlight their relevance for the post-transcriptional regulation of chloroplast gene expression and their role in controlling plant development, stress reactions, and acclimation processes. |
| 学科主题 | Genetics & Heredity |
| 出版地 | BASEL |
| 电子版国际标准刊号 | 2073-4425 |
| WOS关键词 | PENTATRICOPEPTIDE REPEAT PROTEIN ; TRANSFER-RNA MODIFICATION ; 25S RIBOSOMAL-RNA ; MESSENGER-RNA ; NUCLEOTIDE-SEQUENCE ; ESCHERICHIA-COLI ; ARABIDOPSIS ; POLYADENYLATION ; METHYLATION ; GENE |
| WOS研究方向 | Science Citation Index Expanded (SCI-EXPANDED) |
| 语种 | 英语 |
| WOS记录号 | WOS:000689207400001 |
| 出版者 | MDPI |
| 资助机构 | DAAD [91692277] ; DFG [TR175] |
| 源URL | [http://ir.ibcas.ac.cn/handle/2S10CLM1/26676]  |
| 专题 | 中科院光生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Bot, Photosynth Res Ctr, Key Lab Photobiol, Beijing 100093, Peoples R China 2.Ludwig Maximilians Univ Munchen, Plant Mol Biol, Fac Biol, Grosshaderner St 2-4, D-82152 Planegg, Germany |
| 推荐引用方式 GB/T 7714 | Manavski, Nikolay,Vicente, Alexandre,Chi, Wei,et al. The Chloroplast Epitranscriptome: Factors, Sites, Regulation, and Detection Methods[J]. GENES,2021,12(8). |
| APA | Manavski, Nikolay,Vicente, Alexandre,Chi, Wei,&Meurer, Jorg.(2021).The Chloroplast Epitranscriptome: Factors, Sites, Regulation, and Detection Methods.GENES,12(8). |
| MLA | Manavski, Nikolay,et al."The Chloroplast Epitranscriptome: Factors, Sites, Regulation, and Detection Methods".GENES 12.8(2021). |
入库方式： OAI收割
来源：植物研究所
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