中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Weighted sum of harmonic signals for direct imaging in magnetic particle imaging

文献类型:期刊论文

作者Liu, Yanjun5,6,7,8,9; Hui, Hui4,5,6; Liu, Sijia3,5,6; Li, Guanghui5,6,7,8,9; Zhang, Bo5,6,7,8,9; Zhong, Jing2; An, Yu5,6,7,8,9; Tian, Jie1,3,5,6,7,8,9
刊名PHYSICS IN MEDICINE AND BIOLOGY
出版日期2023-07-01
卷号68期号:1页码:13
ISSN号0031-9155
关键词magnetic particle imaging short-time fourier transform direct imaging multi-patch imaging
DOI10.1088/1361-6560/aca9b9
通讯作者Hui, Hui(hui.hui@ia.ac.cn) ; Tian, Jie(tian@ieee.org)
英文摘要Objective. Magnetic particle imaging (MPI) is a novel radiation-free medical imaging modality that can directly image superparamagnetic iron oxide tracers (SPIOs) with high sensitivity, temporal resolution, and good spatial resolution. The MPI reconstruction task can be formulated mathematically as a Fredholm integral problem, but the concrete inversion is not easily possible because of the particle dynamics or scanner issues. Measurement based system matrix inversion takes these factors into account, but prior measurement and calibration are time consuming. Approach. We proposed a direct imaging method based on the weighted sum of harmonic signals. The harmonic signals with spatial information are obtained by the short-time Fourier transform, and odd harmonic components are selected for recombination and then mapped to the sampling trajectory to image the concentration distribution of SPIOs. In addition, we adopt a normalized-weighted sum of harmonics to improve the resolution of the native image. Main results. The effectiveness of the proposed method is verified by simulation imaging experiments and our in-house scanner-based experiments. Quantitative evaluation results show that compared with traditional methods, the structural similarity improved by 48%, mean square error decreased by 88%, and signal-to-artifact ratio increased by 2.5 times. Significance. The proposed method can rapidly image the concentration distribution of nanoparticles without any prior calibration measurements and reduce the blur of MPI images without deconvolution, which has the potential to be implemented as a multi-patch imaging method in MPI.
WOS关键词RECONSTRUCTION ; NANOPARTICLE ; PERFORMANCE ; AMPLITUDE ; TRACER ; MOTION
资助项目National Key Research and Development Program of China[2017YFA0700401] ; National Natural Science Foundation of China[62027901] ; National Natural Science Foundation of China[81827808] ; National Natural Science Foundation of China[81930053] ; National Natural Science Foundation of China[81227901] ; CAS Youth Innovation Promotion Association[2018167] ; CAS Key Technology Talent Program ; Guangdong Key Research and Development Program of China[2021B0101420005] ; Project of High-Level Talents Team Introduction in Zhuhai City[Zhuhai HLHPTP201703]
WOS研究方向Engineering ; Radiology, Nuclear Medicine & Medical Imaging
语种英语
出版者IOP Publishing Ltd
WOS记录号WOS:000904747700001
资助机构National Key Research and Development Program of China ; National Natural Science Foundation of China ; CAS Youth Innovation Promotion Association ; CAS Key Technology Talent Program ; Guangdong Key Research and Development Program of China ; Project of High-Level Talents Team Introduction in Zhuhai City
源URL[http://ir.ia.ac.cn/handle/173211/51081]  
专题自动化研究所_中国科学院分子影像重点实验室
通讯作者Hui, Hui; Tian, Jie
作者单位1.Jinan Univ, Zhuhai Peoples Hosp, Zhuhai Precis Med Ctr, Zhuhai 519000, Peoples R China
2.Beihang Univ, Sch Instrumentat & Optoelect Engn, Beijing 100191, Peoples R China
3.Southeast Univ, Sch Comp Sci & Engn, Nanjing 210096, Peoples R China
4.Univ Chinese Acad Sci, Beijing, Peoples R China
5.Beijing Key Lab Mol Imaging, Beijing 100190, Peoples R China
6.Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
7.Beihang Univ, Key Lab Big Data Based Precis Med, Minist Ind & Informat Technol Peoples Republ China, Beijing 100191, Peoples R China
8.Beihang Univ, Sch Engn Med, Beijing 100191, Peoples R China
9.Beihang Univ, Sch Biol Sci & Med Engn, Beijing 100191, Peoples R China
推荐引用方式
GB/T 7714
Liu, Yanjun,Hui, Hui,Liu, Sijia,et al. Weighted sum of harmonic signals for direct imaging in magnetic particle imaging[J]. PHYSICS IN MEDICINE AND BIOLOGY,2023,68(1):13.
APA Liu, Yanjun.,Hui, Hui.,Liu, Sijia.,Li, Guanghui.,Zhang, Bo.,...&Tian, Jie.(2023).Weighted sum of harmonic signals for direct imaging in magnetic particle imaging.PHYSICS IN MEDICINE AND BIOLOGY,68(1),13.
MLA Liu, Yanjun,et al."Weighted sum of harmonic signals for direct imaging in magnetic particle imaging".PHYSICS IN MEDICINE AND BIOLOGY 68.1(2023):13.

入库方式: OAI收割

来源:自动化研究所

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